1356960

Leflunomide

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 5-Methylisoxazole-4-(4-trifluoromethyl)carboxanilide
• Empirical Formula (Hill Notation): C₁₂H₉F₃N₂O₂
• CAS Number: 75706-12-6
• Molecular Weight: 270.21
• NACRES: NA.24
• PubChem Substance ID: 329750235
• UNSPSC Code: 41116107
• MDL number: MFCD00867593

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: leflunomide
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: Cc1oncc1C(=O)Nc2ccc(cc2)C(F)(F)F
• InChI: 1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)
• InChI key: VHOGYURTWQBHIL-UHFFFAOYSA-N
• Gene Information: human ... DHODH(1723)

Description

General description

Leflunomide is a drug with cytotoxic properties.[1] It is generally used as an immunosuppressive agent.[2]

Application

Leflunomide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H315,H319,H335
• pcodes: P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• flash_point_f: Not applicable
• flash_point_c: Not applicable