U116

U-99194 maleate salt

≥98% (HPLC), solid

• Synonym(s): 5,6-Dimethoxy-2-(di-n-propylamino)indan maleate salt
• Empirical Formula (Hill Notation): C₁₇H₂₇NO₂ · C₄H₄O₄
• CAS Number: 234757-41-6
• Molecular Weight: 393.47
• NACRES: NA.77
• PubChem Substance ID: 24277946
• UNSPSC Code: 12352200
• MDL number: MFCD01529985
• Assay: ≥98% (HPLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: H₂O: >5 mg/mL
• SMILES string: OC(=O)\C=C/C(O)=O.CCCN(CCC)C1Cc2cc(OC)c(OC)cc2C1
• InChI: 1S/C17H27NO2.C4H4O4/c1-5-7-18(8-6-2)15-9-13-11-16(19-3)17(20-4)12-14(13)10-15;5-3(6)1-2-4(7)8/h11-12,15H,5-10H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: FSIQDESGRQTFNN-BTJKTKAUSA-N
• Gene Information: human ... DRD3(1814)

Description

Application

U-99194 maleate has been used as a dopaminergic antagonist to study its effects on immobility episodes[1] and yawning frequency[2] in rats.

Biochem/physiol Actions

U-99194 is a putative D₃ antagonist with a 30-fold preference for the dopamine D₃ vs. D₂ receptor.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

U-99194 maleate salt is soluble in water at a concentration >5 mg/ml.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)