![O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt ≥95%, solid](/deepweb/assets/sigmaaldrich/product/structures/145/804/c567289c-d56d-4488-83ab-a90969f04237/640/c567289c-d56d-4488-83ab-a90969f04237.png)
We do not have any information about the stability of the product: The product is very labile in solution (1.5 days half-life in tissue culture medium) and is readily hydrolyzed below pH 6.0.
T8543
O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt
synthetic (organic), ≥95%, phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor, solid
Synonym(s):
D609
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | CZK 6,460.00 CZK 5,491.00 |
25 mg | Please contact Customer Service for Availability | CZK 26,000.00 |
About This Item
Empirical Formula (Hill Notation):
C11H15KOS2
CAS Number:
Molecular Weight:
266.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106300
EC Number:
280-379-9
MDL number:
Assay:
≥95%
Form:
solid
CZK 5,491.00
List PriceCZK 6,460.00Save 15%Please contact Customer Service for Availability
Product Name
O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt, ≥95%, solid
biological source
synthetic (organic)
Quality Segment
assay
≥95%
form
solid
color
off-white to yellow
solubility
H2O: soluble 50 mg/mL, clear to slightly hazy, colorless to faintly yellow, acetone: easily soluble, diethyl ether: insoluble, hydrocarbons: insoluble
SMILES string
[K]SC(=S)OC1CC2CC1C3CCCC23
InChI
1S/C11H16OS2.K/c13-11(14)12-10-5-6-4-9(10)8-3-1-2-7(6)8;/h6-10H,1-5H2,(H,13,14);/q;+1/p-1/t6-,7?,8?,9-,10?;/m1./s1
InChI key
IGULCCCBGBDZKQ-HJPGVBIPSA-M
Application
Biochem/physiol Actions
D609 can block the production of diacylglycerol (DAG) in the cell. D609 functions by inhibiting the phospholipase C-mediated hydrolysis of the phosphate bond present in phosphatidylcholine and other glycerophospholipids.
Phosphatidylcholine-specific phospholipase C (PLC) and HIV-1 inhibitor. Xanthogenate derivative with in vitro anti-tumor activity.
Preparation Note
O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate or D609 is soluble in water at 50 mg/ml and yields a clear to slightly hazy, colorless to light yellow solution. It is also soluble in acetone. However, it is insoluble in ether and hydrocarbons.
Alcoholic solutions should not be prepared due to the possibility of transesterification. The product is very labile in solution (1.5 days half-life in tissue culture medium) and is readily hydrolyzed below pH 6.0. Hence, solutions should be prepared immediately before use and unused solutions must be discarded. For tissue culture preparations, the media should be buffered to pH 6.0-7.5. HEPES buffer must not be used as it renders this product toxic.
Alcoholic solutions should not be prepared due to the possibility of transesterification. The product is very labile in solution (1.5 days half-life in tissue culture medium) and is readily hydrolyzed below pH 6.0. Hence, solutions should be prepared immediately before use and unused solutions must be discarded. For tissue culture preparations, the media should be buffered to pH 6.0-7.5. HEPES buffer must not be used as it renders this product toxic.
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥95% | assay ≥95% (HPLC) | assay ≥97% (HPLC) | assay ≥98% (HPLC) |
| form solid | form solid | form solid | form solid |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| solubility H2O: soluble 50 mg/mL, clear to slightly hazy, colorless to faintly yellow, diethyl ether: insoluble, hydrocarbons: insoluble, acetone: easily soluble | solubility H2O: soluble, methanol: soluble | solubility 0.1 M HCl: slightly soluble, 0.1 M NaOH: slightly soluble, DMSO: soluble, H2O: insoluble, ethanol: soluble, ethyl acetate: soluble | solubility 0.1 M HCl: slightly soluble, 0.1 M NaOH: slightly soluble, DMSO: soluble, H2O: insoluble, ethanol: soluble, ethyl acetate: soluble |
| color off-white to yellow | color white to off-white | color pale yellow | color pale yellow |
| biological source synthetic (organic) | biological source - | biological source synthetic (organic) | biological source synthetic (organic) |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Hemos adquirido un vial de 5mg para nuestro laboratorio del IIER-ISCIII. Necesitamos saber en qué debe ser disuelto el producto, ya que se indica que es soluble en agua a 50mg/mL. Es estable? cómo debe almacenarse?
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Helpful?
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