T2820

Tazobactam sodium salt

β-lactamase inhibitor

• Synonym(s): CL-298741, YTR-830H, [2S-(2α, 3β, 5α)]-3-Methyl-7-oxo-3(1H,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
• Empirical Formula (Hill Notation): C₁₀H₁₁N₄NaO₅S
• CAS Number: 89785-84-2
• Molecular Weight: 322.27
• NACRES: NA.85
• PubChem Substance ID: 329826726
• UNSPSC Code: 51282127
• MDL number: MFCD00917472

Properties

• Quality Segment: 100
• form: powder or crystals
• color: white to off-white
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: cell wall synthesis | interferes
• SMILES string: [Na+].C[C@]2(Cn1ccnn1)[C@@H](N3[C@@H](CC3=O)S2(=O)=O)C([O-])=O
• InChI: 1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1
• InChI key: RFMIKMMOLPNEDG-QVUDESDKSA-M

Description

General description

Chemical structure: β-lactam

Application

Tazobactam is an antibacterial penicillin derivative which inhibits the action of bacterial β-lactamases. It is used in combination with piperacillin and other β-lactam antibiotics to broaden their spectrum and enhance their effect[1][2]. It is used for bacterial β-lactamase and penicillinase inhibition studies.

Biochem/physiol Actions

Tazobactam is a β -Lactamase inhibitor. When used with β-lactam antibiotics I, it enhances their effect.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)