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SML3711

DENSPM tetrahydrochloride

≥98% (HPLC)

Synonym(s):

BE 333 HCl, BENSpm HCl, DENSpm 4HCl, N1,N11-Diethylnorspermine tetrahydrochloride, N1,N11-bis(ethyl)norspermine tetrahydrochloride

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About This Item

Empirical Formula (Hill Notation):
C13H32N4· 4HCl
CAS Number:
Molecular Weight:
390.26
UNSPSC Code:
41121800
NACRES:
NA.21
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

DENSPM HCl is a nontoxic polyamine analog that enhances polyamine catabolism and production of hazardous hydrogen peroxide and N-acetyl-3-aminopropanal by inducing spermidine/spermine-N1-acetyl transferase (SSAT) expression. DENSPM HCl improves stem cell maintenance through reduced translation, exhibits slower proliferation rates in cancer cells, and induces autophagy. It shows greater antitumor activity and less associated toxicity in a human melanoma xenograft model.
Polyamine pathway inhibitor; potent inducer of spermidine/spermine N1-acetyltransferase

Disclaimer

Hygroscopic

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This Item
S287685605S1141
description

≥98% (HPLC)

description

powder or crystals

description

BioUltra, Molecular Biology, ≥99.5% (AT)

description

BioReagent, Molecular Biology

form

powder

form

powder or crystals

form

powder

form

solid

assay

≥98% (HPLC)

assay

-

assay

≥99.5% (AT)

assay

-

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

300

storage temp.

-10 to -25°C

storage temp.

room temp

storage temp.

-

storage temp.

room temp

solubility

H2O: 2 mg/mL, clear

solubility

water, high purity: 100 mg/ml

solubility

H2O: 1 m at 20 °C, clear, colorless to almost colorless

solubility

H2O: soluble 100 mg/mL, clear, colorless to light yellow

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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