Skip to Content
Merck

85605

Spermine tetrahydrochloride

BioUltra, Molecular Biology, ≥99.5% (AT)

Synonym(s):

N,N′-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride

Slide 1 of 1
Sign In to View Organizational & Contract Pricing.

Select a Size

1 G

CZK 2,420.00

5 G

CZK 8,310.00

25 G

CZK 30,000.00

CZK 2,420.00

Please contact Customer Service for Availability
​
Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):
C10H26N4 · 4HCl
CAS Number:
306-67-2
Molecular Weight:
348.18
UNSPSC Code:
12352116
NACRES:
NA.26
PubChem Substance ID:
57653056
EC Number:
206-189-8
Beilstein/REAXYS Number:
3911771
MDL number:
MFCD00012914
Assay:
≥99.5% (AT)
Form:
powder
Quality level:
300

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

Molecular Biology

Quality Level

300

product line

BioUltra

assay

≥99.5% (AT)

form

powder

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

pH

4.5-7.0 (25 °C, 1 M in H2O)

mp

310-311 °C (dec.) (lit.)

solubility

H2O: 1 m at 20 °C, clear, colorless to almost colorless

anion traces

sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.2, λ: 280 nm Amax: 0.15

SMILES string

Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN

InChI

1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H

InChI key

XLDKUDAXZWHPFH-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
85610S28765677
Spermine tetrahydrochloride BioUltra, Molecular Biology, ≥99.5% (AT)

Sigma-Aldrich

85605

Spermine tetrahydrochloride

Spermine tetrahydrochloride ≥99.0% (AT), powder or crystals

Sigma-Aldrich

85610

Spermine tetrahydrochloride

Spermine tetrahydrochloride powder or crystals

Sigma-Aldrich

S2876

Spermine tetrahydrochloride

Spermine, Tetrahydrochloride

Sigma-Aldrich

5677

Spermine, Tetrahydrochloride

form

powder

form

powder or crystals

form

powder or crystals

form

solid

assay

≥99.5% (AT)

assay

≥99.0% (AT)

assay

-

assay

≥99% (titration)

Quality Level

300

Quality Level

300

Quality Level

200

Quality Level

100

solubility

H2O: 1 m at 20 °C, clear, colorless to almost colorless

solubility

H2O: 0.1 g/mL, clear

solubility

water, high purity: 100 mg/ml

solubility

water: 20 mg/mL

grade

for molecular biology

grade

-

grade

-

grade

-

product line

BioUltra

product line

-

product line

-

product line

-

Application

Used to precipitate DNA from low salt aqueous buffers.

Biochem/physiol Actions

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Mixed NMDA agonist/antagonist at the polyamine site. Role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Other Notes

Spermine precipitation of DNA.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCB4115
BCCN3270
BCCM7832
BCCM0242
BCCK8782

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Spermine precipitation of DNA.
D.M. Wallace
Methods in Enzymology, 152, 46-46 (1987)
Naoki Ochi
Journal of chromatography. A, 1601, 115-120 (2019-06-24)
A simple and accurate method was developed for the quantitative determination of eight biogenic amines (cadaverine, histamine, 2-phenylethylamine, putrescine, spermidine, spermine, tryptamine, and tyramine) in salted mackerel fillet. The eight biogenic amines in the samples were extracted with 5% trichloroacetic
Desiree Bailey et al.
Pharmacology, biochemistry, and behavior, 133, 57-64 (2015-04-01)
The aim of this study was to examine the acute effect of a range of novel hydroxycinnamic acid derivatives of spermine on the development of spermine-induced CNS excitation and convulsions in female Laca mice, and to assess the chronic adverse
Yong Kee Choi et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 19(2), 77-84 (2008-10-11)
Levels of ionotropic glutamate (Glu) N-methyl-d-aspartic acid (NMDA), 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA), and kainic acid (KA) receptors in forebrain regions of juvenile rats (age 42 days) were quantified after 3 weeks of treatment with three different doses of risperidone (0.3, 1.0
Enzo Agostinelli et al.
International journal of oncology, 45(3), 1109-1122 (2014-06-28)
It has been confirmed that multidrug resistant (MDR) melanoma cells (M14 ADR2) are more sensitive than their wild-type counterparts (M14 WT) to H2O2 and aldehydes, the products of bovine serum amine oxidase (BSAO)-catalyzed oxidation of spermine. The metabolites formed by
View All Related Papers

Global Trade Item Number

SKUGTIN
85605-25G04061833417904
85605-1G04061833026540
85605-5G04061833026601

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service