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SML3430

Benvitimod

≥98% (HPLC), AHR immunomodulator, powder

Synonym(s):

(E)-2-Isopropyl-5-styrylbenzene-1,3-diol, 3,5-Dihydroxy-4-isopropyl-trans-stilbene, 3,5-Dihydroxy-4-isopropylstilbene, GSK-2894512, Tapinarof, WBI 1001

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Size/SKUAvailabilityPrice
10 mg
Please contact Customer Service for Availability
CZK 1,560.00
50 mg
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CZK 6,300.00

About This Item

Empirical Formula (Hill Notation):
C17H18O2
CAS Number:
Molecular Weight:
254.32
NACRES:
NA.77
UNSPSC Code:
41121706
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

CZK 1,560.00


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Product Name

Benvitimod, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

, White to Very dark grey

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

CC(C1=C(C=C(C=C1O)/C=C/C2=CC=CC=C2)O)C

InChI

1S/C17H18O2/c1-12(2)17-15(18)10-14(11-16(17)19)9-8-13-6-4-3-5-7-13/h3-12,18-19H,1-2H3/b9-8+

InChI key

ZISJNXNHJRQYJO-CMDGGOBGSA-N

Biochem/physiol Actions

Aryl hydrocarbon receptor (AHR) immunomodulator that inhibits skin inflammation and enhances skin barrier function.
Benvitimod (Tapinarof) is an aryl hydrocarbon receptor (AHR) immunomodulator that inhibits skin inflammation and enhances skin barrier function. Benvitimod is a metabolite, similar to resveratrol, produced by bacterial symbionts of entomopathogenic nematodes. It induces downregulation of inflammatory cytokines such as IL-17A, IL-17F, IL-19, IL-22, IL-23, and IL-1. Benvitimod also induces the expression of skin barrier genes related to keratinocyte differentiation.

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This Item
SML2226PZ0037SML2814
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

, White to Very dark grey

color

white to beige

color

white to beige

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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