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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 mg | Please contact Customer Service for Availability | CZK 2,360.00 | |
| 50 mg | Please contact Customer Service for Availability | CZK 7,640.00 |
About This Item
Empirical Formula (Hill Notation):
C19H21N3O2
CAS Number:
Molecular Weight:
323.39
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
[n]1(c(ncc1c3ccc(cc3)OC)NCc2cc(ccc2)OC)C
InChI
1S/C19H21N3O2/c1-22-18(15-7-9-16(23-2)10-8-15)13-21-19(22)20-12-14-5-4-6-17(11-14)24-3/h4-11,13H,12H2,1-3H3,(H,20,21)
InChI key
LCVOJBGSGIOMKF-UHFFFAOYSA-N
Biochem/physiol Actions
MALAT1-IN-5 reduces the long noncoding (lnc) RNA metastasis-associated lung adenocarcinoma transcript 1 (Malat1) level (by 54% in 7 days at 1 μM; MMTV-PyMT tumors organoids) via specific interaction with Malat1 triple-helical configuration of 3′-terminal element for nuclear expression (ENE KD = 2.9 μM under physiologic ionic conditions), but not the homologous 3′-end triple-helix of Neat1 (MENβ) lncRNA. MALAT1-IN-5 decreases MMTV-PyMT organoid branching morphogenesis (by 38% in 7 days at 1 μM) and modulates the levels of Malat1-targeted mRNAs Krt16 & Csn2.
Selective metastasis-associated lung adenocarcinoma transcript 1 inhibitor that decreases tumor organoid branching and modulates Malat1-targeted mRNAs.
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form solid |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 10 mg/mL, clear | solubility DMSO: >20 mg/mL, H2O: >20 mg/mL |
| color white to beige | color white to beige | color white to beige | color white |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML2806-50MG | 04061842461349 |
| SML2806-10MG | 04061842461332 |



