SML2402
WYC-209
≥98% (HPLC)
Synonym(s):
2-[2-(3,4-Dihydro-4,4-dimethyl-1-oxido-2H-1-benzothiopyran-6-yl)ethynyl-5-pyrimidinecarboxylic acid, ethyl ester
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 mg | Please contact Customer Service for Availability | CZK 7,900.00 CZK 6,715.00 |
About This Item
Empirical Formula (Hill Notation):
C20H20N2O3S
CAS Number:
Molecular Weight:
368.45
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
CZK 6,715.00
List PriceCZK 7,900.00Save 15%Please contact Customer Service for Availability
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=S1CCC(C)(C)C2=C1C=CC(C#CC3=NC=C(C(OCC)=O)C=N3)=C2
InChI key
LLMDAYVUHYVJSS-UHFFFAOYSA-N
Biochem/physiol Actions
Synthetic retinoid with antiproliferative activity
WYC-209 is a synthetic retinoid with antiproliferative activity and better inhibition of cancer cell growth and proliferation than Tazarotene or ATRA (all-trans-retinoic acid). WYC-209 was shown to inhibit proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 value of 190 nM and also inhibited proliferation of TRCs of human melanoma, lung cancer, ovarian cancer, and breast cancer in culture.
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This Item | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: ≥20 mg/mL | solubility DMSO: 1 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear |
| color white to beige | color white to off-white | color white to light brown | color white to beige |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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