Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP12 interacts with nsp7 and nsp8.
Immunogen
Anti-SARS-CoV-2 (COVID-19) NSP12 antibody was raised against a peptide corresponding to 16 amino acids near the carboxyl terminus of SARS-CoV-2 (COVID-19) NSP12 protein. The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) NSP12 protein.
Application
Antibody validated: SARS-CoV-2 (COVID-19) NSP12 antibody can detect 2 ng of free peptide at 1 μg/mL in ELISA. It can detect SARS-CoV-2 NSP12 recombinant protein by ELISA and WB. All other applications and species not yet tested.
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