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(±)-6-Chloro-PB hydrobromide

Name: (±)-6-Chloro-PB hydrobromide
Brand: SIGMA
Price: 5746 CZK

≥98% (HPLC), D1 dopamine receptor agonist, solid

Synonym(s):

(±)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, (±)-SKF-81297 hydrobromide

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Size/SKU	Availability	Price
25 mg	Please contact Customer Service for Availability	CZK 6,760.00 CZK 5,746.00

About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₆ClNO₂ · HBr

CAS Number:

71636-61-8

Molecular Weight:

370.67

UNSPSC Code:

12352200

PubChem Substance ID:

24277934

NACRES:

NA.77

MDL number:

MFCD00153782

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

desiccated

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Properties

Product Name

(±)-6-Chloro-PB hydrobromide, ≥98% (HPLC), solid

Quality Segment

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to light tan

solubility

H₂O: 1.7 mg/mL, DMSO: >10 mg/mL, ethanol: 6.3 mg/mL

SMILES string

Br[H].Oc1cc2C(CNCCc2c(Cl)c1O)c3ccccc3

InChI

1S/C16H16ClNO2.BrH/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20;/h1-5,8,13,18-20H,6-7,9H2;1H

InChI key

RMIJGBMRNYUZRG-UHFFFAOYSA-N

Gene Information

human ... DRD1(1812)

Description

Application

(±)-6-Chloro-PB hydrobromide has been used as a dopamine D1 receptor (Drd1a) agonist to study the role of the drd1a-dopamine receptor inactivation of extracellular signal‑regulated protein kinase 1/2 (ERK1/2) in the wild-type and striatum of dopamine-depleted mice.[1] It has also been used as a Drd1a agonist to identify the contribution of D1 (D1R)-like dopamine receptor signaling on learning and memory in Barnes maze in rats.[2]

Biochem/physiol Actions

(+/-)-6-Chloro-PB HBr is a full D₁ dopamine receptor agonist.

Disclaimer

Product is air and light sensitive

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Show Differences

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This Item	C130	S2816	D054
Sigma-Aldrich S143 (±)-6-Chloro-PB hydrobromide	Sigma-Aldrich C130 Chloro-APB hydrobromide	Sigma-Aldrich S2816 SKF-83959 hydrobromide	Sigma-Aldrich D054 R(+)-SCH-23390 hydrochloride
form solid	form solid	form solid	form solid
assay ≥98% (HPLC)	assay -	assay ≥98% (HPLC)	assay ≥98% (HPLC)
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage condition desiccated	storage condition -	storage condition -	storage condition desiccated, protect from light
solubility H₂O: 1.7 mg/mL, ethanol: 6.3 mg/mL, DMSO: >10 mg/mL	solubility H₂O: 3.7 mg/mL, aqueous base: unstable, ethanol: soluble	solubility DMSO: >20 mg/mL, H₂O: insoluble	solubility H₂O: >5 mg/mL
color white to light tan	color tan	color white	color white

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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