PLA0283

Rabbit anti-TSG101 Antibody, Affinity Purified

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• Synonym(s): ESCRT-I complex subunit TSG101, TSG10, VPS23, tumor susceptibility gene 10, tumor susceptibility gene 101, tumor susceptibility protein
• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: -

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: mouse, human
• technique(s): western blot: 1:2,000-1:10,000
• accession no.: NP_006283.1
• UniProt accession no.: Q99816
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... TSG101(7251)

Description

Immunogen

The epitope recognized by PLA0283 maps to a region between residue 300 and 350 of human Tumor Susceptibility Gene 101 using the numbering given in entry NP_006283.1 (GeneID 7251).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Tumor susceptibility gene 101 protein (TSG101) is a component of the ESCRT-I complex, a regulator of vesicular trafficking process. TSG101 mediates the association between the ESCRT-0 and ESCRT-I complex. TSG101 binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). TSG101, along with CEP55, is required for completion of cytokinesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99816].

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable