P7742
Prostaglandin G2
≥95% (HPLC), acetone solution
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About This Item
Empirical Formula (Hill Notation):
C20H32O6
CAS Number:
Molecular Weight:
368.46
UNSPSC Code:
12352204
PubChem Substance ID:
EC Number:
200-662-2
MDL number:
Quality Level
assay
≥95% (HPLC)
form
acetone solution
shipped in
dry ice
storage temp.
−70°C
SMILES string
CCCCC[C@H](OO)\C=C\[C@H]1C2CC(OO2)[C@@H]1C\C=C/CCCC(O)=O
InChI
1S/C20H32O6/c1-2-3-6-9-15(24-23)12-13-17-16(18-14-19(17)26-25-18)10-7-4-5-8-11-20(21)22/h4,7,12-13,15-19,23H,2-3,5-6,8-11,14H2,1H3,(H,21,22)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
InChI key
SGUKUZOVHSFKPH-YNNPMVKQSA-N
Biochem/physiol Actions
Aryl hydrocarbon receptor (AhR) ligand and activator of the AhR signal transduction pathway. Also shown to activate nitric oxide synthase (NOS) in rat brain synaptosomal membrane fractions.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
target_organs
Central nervous system
supp_hazards
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
1.4 °F - closed cup
flash_point_c
-17 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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M d'Ischia et al.
Nitric oxide : biology and chemistry, 4(1), 4-14 (2000-03-29)
Under aerobic conditions, exposure of peroxidized lipids to nitric oxide (NO) was found to result in a rapid decrease in the levels of thiobarbituric acid-reactive substances (TBARS). Addition of 10-100 microM NO to rat brain homogenates preincubated for 2 h
T E Eling et al.
The Journal of biological chemistry, 266(19), 12348-12355 (1991-07-05)
Prostaglandin H synthase oxidizes arachidonic acid to prostaglandin G2 (PGG2) via its cyclooxygenase activity and reduces PGG2 to prostaglandin H2 by its peroxidase activity. The purpose of this study was to determine if endogenously generated PGG2 is the preferred substrate
Formation of electronically excited states during the oxidation of arachidonic acid by prostaglandin endoperoxide synthase.
E Cadenas et al.
Methods in enzymology, 319, 67-77 (2000-07-25)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P7742-500UG | 04061838164698 |