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P4505

Protamine sulfate

powder

Synonym(s):

Clupeine

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Size/SKUAvailabilityPrice
1 g
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CZK 1,420.00
5 g
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CZK 3,550.00
25 g
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CZK 14,100.00

About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:

CZK 1,420.00


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Product Name

Protamine sulfate salt from herring, Grade III, histone, free(Millon test)

biological source

fish (herring)

Quality Segment

type

Grade III

form

powder

impurities

histone, free (Millon test)

solubility

6 M HCl: 25 mg/mL, clear, colorless to very faintly yellow

Application

May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer.

Biochem/physiol Actions

Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase.

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This Item
P4380P4020P4005
biological source

fish (herring)

biological source

fish (salmon)

biological source

-

biological source

fish (salmon)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

amorphous powder

form

solid

solubility

6 M HCl: 25 mg/mL, clear, colorless to very faintly yellow

solubility

6 M HCl: 25 mg/mL, clear, colorless to light yellow

solubility

6 M HCl: 25 mg/mL

solubility

H2O: soluble, clear to slightly hazy, colorless to faintly yellow

type

Grade III

type

Grade II

type

Grade X

type

Grade IV

impurities

histone, free (Millon test)

impurities

-

impurities

histone, free (Millon test)

impurities

Histone, free (Millon test)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

  1. Is it possible to confirm whether product P4505 contains salts (Mg+2, Na+) as impurities or due to its origin?

    1 answer
    1. There is no information regarding the presence of other salts, as the product is currently sourced from an external supplier(s). The supplier's Certificate of Analysis does not mention the testing for salts such as magnesium or calcium.

      Helpful?

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