M6699

Maslinic acid

≥98% (HPLC)

• Synonym(s): 2α,3β-Dihydroxyolean-12-en-28-oic acid, 2α-Hydroxyoleanolic acid, Crategolic acid
• Empirical Formula (Hill Notation): C₃₀H₄₈O₄
• CAS Number: 4373-41-5
• Molecular Weight: 472.70
• NACRES: NA.25
• PubChem Substance ID: 329818034
• UNSPSC Code: 12352205
• MDL number: MFCD00049293

Properties

• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: acetone: 1 mg/mL, clear, colorless
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O
• InChI: 1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1
• InChI key: MDZKJHQSJHYOHJ-LLICELPBSA-N

Description

General description

Maslinic acid is a pentacyclic triterpene compound first isolated from Crataegus oxyacantha L.[1] It is primarily sourced from Olea europaea L.[1] and can be found in the non-glyceride fraction of olive pomace.[2]

Application

Maslinic acid has been used to study its antiproliferative and antiangiogenic effects on human renal cell carcinoma (RCC) cell lines and endothelial cells, respectively.[3] It has also been used as a reference standard to extract triterpenoic acids from olive pomace using the microwave-assisted extraction (MAE) method.

Biochem/physiol Actions

Maslinic acid is a potent antioxidant and anti-inflammatory agent.[1][2] Other than being an excellent anti-cancer agent, it also displays anti-diabetic, and anti-parasitic properties.[1] Maslinic acid exerts neuroprotective and cardioprotective effects.[1] It has been reported to be a multi-targeted antimalarial drug against Plasmodium falciparum.[4]

Predominant triterpenoid found in olives. Anti-proliferative. Promising chemopreventive agent.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable