M4699

MTEP hydrochloride

≥98% (HPLC), mGlu5 antagonist,

• Synonym(s): MTEP hydrochloride, 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine hydrochloride
• Empirical Formula (Hill Notation): C₁₁H₈N₂SHCl
• CAS Number: 1186195-60-7
• Molecular Weight: 236.72
• UNSPSC Code: 12352200
• PubChem Substance ID: 329817993
• NACRES: NA.77
• MDL number: MFCD08458895
• Assay: ≥98% (HPLC)
• Storage condition: desiccated

Properties

• Product Name: MTEP hydrochloride, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 30 mg/mL, clear
• originator: Merck & Co., Inc., Kenilworth, NJ, U.S.
• storage temp.: 2-8°C
• SMILES string: Cl.Cc1nc(cs1)C#Cc2cccnc2
• InChI: 1S/C11H8N2S.ClH/c1-9-13-11(8-14-9)5-4-10-3-2-6-12-7-10;/h2-3,6-8H,1H3;1H
• InChI key: YCIOJDKGCWAHLR-UHFFFAOYSA-N

Description

Biochem/physiol Actions

MTEP is a potent and highly selective antagonist for mGluR5.

MTEP is a selective mGlu5 antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable