M103

1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride

solid

• Synonym(s): 2′-Methyl-MPTP hydrochloride
• Empirical Formula (Hill Notation): C₁₃H₁₇N · HCl
• CAS Number: 127382-79-0
• Molecular Weight: 223.74
• NACRES: NA.77
• PubChem Substance ID: 329817848
• UNSPSC Code: 12352200
• MDL number: MFCD00055222
• Form: solid

Properties

• form: solid
• Quality Segment: 100
• color: white
• solubility: H₂O: soluble, ethanol: soluble
• SMILES string: Cl[H].CN1CCC(=CC1)c2ccccc2C
• InChI: 1S/C13H17N.ClH/c1-11-5-3-4-6-13(11)12-7-9-14(2)10-8-12;/h3-7H,8-10H2,1-2H3;1H
• InChI key: QLIQCKBPYIWPTE-UHFFFAOYSA-N

Description

Application

1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride has been used to study its effect on core temperature in C57BL/6J mice.

Biochem/physiol Actions

1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride (MPTP) is a tertiary amine. It is widely used to induce experimental parkinsonism in mice.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges