M006

Proglumide sodium salt

Name: Proglumide sodium salt
Brand: SIGMA
Price: 4460 CZK

solid

Synonym(s):

4-Benzoylamino-5-dipropylamino-5-oxopentanoic acid sodium-potassium salt, N-Benzoyl-N′,N′-dipropyl-DL-isoglutamine sodium-potassium salt

Slide 1 of 3

Select a Size

100 MG

CZK 4,460.00

500 MG

CZK 24,055.00

CZK 4,460.00

Please contact Customer Service for Availability

Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₅N₂NaO₄

CAS Number:

99247-33-3

Molecular Weight:

356.39

NACRES:

NA.77

PubChem Substance ID:

24896533

UNSPSC Code:

12352200

MDL number:

MFCD00069301

Form:

solid

Quality level:

100

Key Documents

View All Documentation

form

solid

Quality Level

100

color

white

solubility

H₂O: soluble

SMILES string

[Na+].CCCN(CCC)C(=O)C(CCC([O-])=O)NC(=O)c1ccccc1

InChI

1S/C18H26N2O4.Na/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14;/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22);/q;+1/p-1

InChI key

UFMWGCINVOIJSO-UHFFFAOYSA-M

Gene Information

human ... CCK(885), CCKAR(886), CCKBR(887)
mouse ... CCK(12424)
rat ... CCK(25298)

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item	Z2001	SML1228	SML1229
Sigma-Aldrich M006 Proglumide sodium salt	Sigma-Aldrich Z2001 Zonisamide sodium salt	Sigma-Aldrich SML1228 Cyclic-di-GMP sodium salt	Sigma-Aldrich SML1229 2′,3′-cGAMP sodium salt
form solid	form powder	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
solubility H₂O: soluble	solubility H₂O: >5 mg/mL	solubility -	solubility -
color white	color white to beige	color white to beige	color white to beige
Gene Information human ... CCK(885), CCKAR(886), CCKBR(887) mouse ... CCK(12424) rat ... CCK(25298)	Gene Information human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)	Gene Information -	Gene Information -

Application

Proglumide sodium salt has been used to study the effects of proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.

Biochem/physiol Actions

Proglumide sodium salt is a non-peptide cholecystokinin receptor antagonist that has greater selectivity for the CCKA subtype. It selectively blocks central nervous system effects. Proglumide sodium salt is orally active.

CCK antagonist; selectively blocks CNS effects.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The effect of centrally administered CCK-receptor antagonists on food intake in rats.

E S Corp et al.

Physiology & behavior, 61(6), 823-827 (1997-06-01)

Cholecystokinin (CCK) receptors are classified as two subtypes, designated CCK(A) and CCK(B), and both subtypes are found in brain and peripheral tissues of rats. CCK-8 has been shown to act peripherally to reduce meal size, and this satiating action can

Role of cholecystokinin and its antagonist proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.

V. C. Rubio

Physiology & Behavior (2008)

The cholecystokinin antagonist, proglumide, increases food intake in the rat

G.Shillabeer and J. Davidson

Regulatory Peptides (1984)

Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes.

James M Hill et al.

Science translational medicine, 6(265), 265ra169-265ra169 (2014-12-05)

Herpesviruses are highly prevalent and maintain lifelong latent reservoirs, thus posing challenges to the control of herpetic disease despite the availability of antiviral pharmaceuticals that target viral DNA replication. The initiation of herpes simplex virus infection and reactivation from latency

Selective monoamine oxidase B inhibition by an Aphanizomenon flos-aquae extract and by its constitutive active principles phycocyanin and mycosporine-like amino acids.

Stefano Scoglio et al.

Phytomedicine : international journal of phytotherapy and phytopharmacology, 21(7), 992-997 (2014-04-03)

Aphanizomenon flos-aquae (AFA) is a fresh water unicellular blue-green alga that has been traditionally used for over 25 years for its health-enhancing properties. Recent studies have shown the ability of a proprietary AFA extract (Klamin(®)) to improve mood, counteract anxiety

View All Related Papers

Global Trade Item Number

SKU	GTIN
M006-500MG	04061832677194
M006-100MG	04061833992500

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Proglumide sodium salt