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L7895

Lipopolysaccharides from Salmonella typhosa

γ-irradiated, BioXtra, suitable for cell culture

Synonym(s):

LPS

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Size/SKUAvailabilityPrice
1 mg
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CZK 1,790.00

About This Item

UNSPSC Code:
12352201
NACRES:
NA.75
MDL number:

CZK 1,790.00


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biological source

bacterial (Salmonella typhosa)

Quality Segment

sterility

γ-irradiated

product line

BioXtra

form

lyophilized powder

purified by

gel-filtration chromatography

technique(s)

cell culture | mammalian: suitable

impurities

<1% Protein (Lowry)

color

white to faint yellow

solubility

water: 0.90-1.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow

storage temp.

2-8°C

Application

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Lipopolysaccharides from Salmonella typhosa are used in cell culture and cell binding applications. The role of LPS in the secretion of TNF-α and IL-6 was studied in mouse spleen cell culture.[1] It was used to study the role of inflammatory responses in multiple sclerosis.[2]

Biochem/physiol Actions

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

Other Notes

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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1 of 1

This Item
L6143L7770L2387
technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

biological source

bacterial (Salmonella typhosa)

biological source

Salmonella enterica (serotype typhimurium)

biological source

Salmonella enterica (Serotype enteritidis)

biological source

bacterial (Salmonella typhosa)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

solubility

water: 0.90-1.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow

solubility

-

solubility

water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless

solubility

water: soluble

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. I would like to know which synonyms are valid for Salmonella typhosa... I try to find if it is a type of S. enterica, S.typhi or something else... but I cannot find it. I guess other names are used for the same organism. Thanks a lot

    1 answer
    1. The synonyms for Salmonella typhosa are Salmonella typhi and typhoid bacillus. The Lipopolysaccharides products offered from Salmonella typhosa are L2387,L7895, and L6386.

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