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I134

L-N5-(1-Iminoethyl)ornithine hydrochloride

≥95% (HPLC)

Synonym(s):

L-NIO hydrochloride, L-Ornithine ψ-acetamidine hydrochloride

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Pack SizeSKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
CZK 10,800.00
CZK 9,180.00
25 mg
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CZK 37,100.00

About This Item

Empirical Formula (Hill Notation):
C7H15N3O2 · xHCl
CAS Number:
852173-80-9
Molecular Weight:
173.21 (free base basis)
NACRES:
NA.26
PubChem Substance ID:
329815348
UNSPSC Code:
12352204
MDL number:
MFCD00153817
Form:
powder
Assay:
≥95% (HPLC)
Mol wt:
calculated mol wt 173.22 g/mol

CZK 9,180.00

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Quality Level

100

assay

≥95% (HPLC)

form

powder

mol wt

calculated mol wt 173.22 g/mol

storage condition

desiccated, under inert gas

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

CC(NCCC[C@H](N)C(O)=O)=N.[H]Cl

InChI

1S/C7H15N3O2.ClH/c1-5(8)10-4-2-3-6(9)7(11)12;/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12);1H/t6-;/m0./s1

InChI key

JIBZSGQTCBWUKL-RGMNGODLSA-N

Application

L-N5-(1-Iminoethyl) ornithine hydrochloride has been used to study the effects of the cytotoxic drug paclitaxel and carbachol (a cholinergic agonist) to induce death in breast tumor MCF-7 cells and the role of nitric oxide synthase (NOS) in this effect. It has also been used to study its effects on pulmonary arterial responses to sufentanil in the feline pulmonary vascular bed.

Biochem/physiol Actions

A potent irreversible inhibitor of nitric oxide synthase.

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This Item
P2533I8021A2636
L-N5-(1-Iminoethyl)ornithine hydrochloride ≥95% (HPLC)

Sigma-Aldrich

I134

L-N5-(1-Iminoethyl)ornithine hydrochloride

Poly-L-ornithine hydrochloride mol wt 15,000-30,000

Sigma-Aldrich

P2533

Poly-L-ornithine hydrochloride

L-N6-(1-Iminoethyl)lysine dihydrochloride

Sigma-Aldrich

I8021

L-N6-(1-Iminoethyl)lysine dihydrochloride

S-(2-Aminoethyl)-L-cysteine hydrochloride ≥98% (TLC)

Sigma-Aldrich

A2636

S-(2-Aminoethyl)-L-cysteine hydrochloride

assay

≥95% (HPLC)

assay

-

assay

≥97% (HPLC)

assay

≥98% (TLC)

mol wt

calculated mol wt 173.22 g/mol

mol wt

15,000-30,000

mol wt

-

mol wt

-

form

powder

form

powder or solid

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

H2O: 2 mg/mL, clear (warmed)

solubility

-

solubility

water: 50 mg/mL, clear, colorless

solubility

-

storage condition

desiccated, under inert gas

storage condition

-

storage condition

-

storage condition

-

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000280829
0000280827
0000246101
0000280827
0000280829

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Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase
Alejandro Javier Espa?ol
International Immunopharmacology, 29(1) (2015)
The effects of sufentanil in the feline pulmonary vascular bed
Alan D Kaye
European Journal of Pharmacology (2006)
International Review of Neurobiology, 42 (1998)

Global Trade Item Number

SKUGTIN
I134-25MG04061833847688
I134-5MG04061833262429
I134-1MG04061833847671

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