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H9627

Sigma-Aldrich

Hematoxylin

Synonym(s):

Natural Black 1

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25 G
CZK 6,240.00
100 G
CZK 18,100.00
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CZK 6,240.00


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25 G
CZK 6,240.00
100 G
CZK 18,100.00
5 X 100 G
CZK 52,500.00

About This Item

Empirical Formula (Hill Notation):
C16H14O6 · xH2O
CAS Number:
Molecular Weight:
302.28 (anhydrous basis)
Colour Index Number:
75290
Beilstein:
91400
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

CZK 6,240.00


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form

powder

Quality Level

technique(s)

titration: suitable

mp

200 °C (dec.) (lit.)

solubility

95% ethanol: 1 mg/mL

SMILES string

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1

InChI key

WZUVPPKBWHMQCE-XJKSGUPXSA-N

Gene Information

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Application

Hematoxylin has been used for staining gastric cancer tissues[1], myocardial tissue[2], heart sections[3] and ovarian nuclei.[4]

Biochem/physiol Actions

Hematoxylin is an organic stain which chelates with metal ions and binds to DNA and RNA. It is used for staining nucleus of the cells.[5] Hematoxylin along with eosin stain is used in the diagnosis of invasion stage in tumors.[6]

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Down-regulation of miR-327 alleviates ischemia/reperfusion-induced myocardial damage by targeting RP105
Yang Y, et al.
Cellular Physiology and Biochemistry, 49(3), 1049-1063 (2018)
Hematoxylin and eosin staining of intact tissues via delipidation and ultrasound
Li Y, et al.
Scientific Reports, 8(1), 12259-12259 (2018)
In Situ Molecular Pathology and Co-Expression Analyses, 81-131 (2013)
A novel human S10F-Hsp20 mutation induces lethal peripartum cardiomyopathy
Liu GS, et al.
Journal of Cellular and Molecular Medicine (2018)
Clinical significance and effect of Sam68 expression in gastric cancer
Xiao J, et al.
Oncology Letters, 15(4), 4745-4752 (2018)

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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