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GW22768

Sigma-Aldrich

Anti-MAPK1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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50 μG
CZK 9,160.00

CZK 9,160.00

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50 μG
CZK 9,160.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CZK 9,160.00

Please contact Customer Service for Availability
Request a Bulk Order

biological source

chicken

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, mouse, human

manufacturer/tradename

Genway 15-288-22768

technique(s)

western blot: suitable

NCBI accession no.

NP_620407.1

UniProt accession no.

P28482

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAPK1(5594)

Immunogen

Immunogen Sequence: GI # 20986531, sequence 232-360
Recombinant mitogen-activated protein kinase 1

Application

Anti-MAPK1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Mitogen-activated protein kinase 1 is an enzyme encoded by the MAPK1 gene in humans. RAS/mitogen - activated protein kinase (MAPK) pathway plays a crucial role in embryonic and postnatal development. It is also associated with COPD (chronic obstructive pulmonary disease) and p38 MAPK may have a a potential target for the treatment of COPD.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
029K1918
039K1928
029K1919

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Natalia Bezniakow et al.
Developmental period medicine, 18(3), 285-296 (2014-09-04)
The RASopathies are a class of developmental syndromes. Each of them exhibits distinctive phenotypic features, although there are numerous overlapping clinical manifestations that include: dysmorphic craniofacial features, congenital cardiac defects, skin abnormalities, varying degrees of intellectual disability and increased risk
Cuiping Huang et al.
Medical science monitor : international medical journal of experimental and clinical research, 19, 1229-1235 (2014-01-03)
Inflammation and remodeling of the small airways are major determinants of the progression and severity of COPD. The present study explored the correlation between sputum p38 mitogen-activated protein kinase (MAPK) activity and airway inflammation and reduction of lung function in

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