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E006

β-Carboline-3-carboxylic acid N-methylamide

Benzodiazepine receptor inverse agonist, solid

Synonym(s):

β-CCA methylamide, FG-7142, N-Methyl-β-carboline-3-carboxamide

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Pack SizeSKUAvailabilityPrice
100 mg
Please contact Customer Service for Availability
CZK 7,050.00
500 mg
Please contact Customer Service for Availability
CZK 24,300.00

About This Item

Empirical Formula (Hill Notation):
C13H11N3O
CAS Number:
78538-74-6
Molecular Weight:
225.25
UNSPSC Code:
12352106
PubChem Substance ID:
24278181
NACRES:
NA.77
MDL number:
MFCD00055075
Form:
solid
Quality level:
100

CZK 7,050.00

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Product Name

β-Carboline-3-carboxylic acid N-methylamide,

form

solid

Quality Level

100

color

light tan

solubility

DMSO: >10 mg/mL, H2O: insoluble

SMILES string

CNC(=O)c1cc2c(cn1)[nH]c3ccccc23

InChI

1S/C13H11N3O/c1-14-13(17)11-6-9-8-4-2-3-5-10(8)16-12(9)7-15-11/h2-7,16H,1H3,(H,14,17)

InChI key

QMCOPDWHWYSJSA-UHFFFAOYSA-N

Gene Information

human ... BZRAP1(9256)

Biochem/physiol Actions

Benzodiazepine inverse receptor agonist; potent anxiogenic agent.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Disclaimer

Solutions may be stored for several days at 4 °C.

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Show Differences

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This Item
SML2372C2020A6226
β-Carboline-3-carboxylic acid N-methylamide

Sigma-Aldrich

E006

β-Carboline-3-carboxylic acid N-methylamide

β-Muricholic Acid ≥98% (HPLC)

Sigma-Aldrich

SML2372

β-Muricholic Acid

α-Cyano-4-hydroxycinnamic acid ≥98% (TLC), powder

Sigma-Aldrich

C2020

α-Cyano-4-hydroxycinnamic acid

AM251 >98% (HPLC), solid

Sigma-Aldrich

A6226

AM251

form

solid

form

powder

form

powder

form

solid

Quality Level

100

Quality Level

-

Quality Level

300

Quality Level

100

solubility

DMSO: >10 mg/mL, H2O: insoluble

solubility

DMSO: 2 mg/mL, clear

solubility

H2O: slightly soluble, methanol: water: soluble, polar organic solvents: soluble

solubility

DMSO: >10 mg/mL, H2O: insoluble

color

light tan

color

white to beige

color

yellow

color

white

Gene Information

human ... BZRAP1(9256)

Gene Information

-

Gene Information

-

Gene Information

mouse ... Cnr1(12801), Cnr2(12802)
rat ... Cnr1(25248)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000515855
0000515855
0000357071
0000357070
0000357071

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Articles

DISCOVER Bioactive Small Molecules for Neuroscience

DISCOVER Bioactive Small Molecules for Neuroscience

Natale R Sciolino et al.
Behavioural brain research, 233(1), 191-200 (2012-05-15)
Although exercise improves anxiety in humans, it is controversial whether exercise is anxiolytic in rodents. We tested the hypothesis that stress influences the effect of exercise on anxiety-like and defensive behaviors. To explore the neurobiological mechanisms of exercise, we also
Hongrun Yu et al.
PloS one, 7(8), e42684-e42684 (2012-08-29)
Post-traumatic stress disorder (PTSD) is an anxiety disorder that not only affects mental health, but may also affect bone health. However, there have been no studies to examine the direct relationship between PTSD and bone. We employed electric shocks in
Philip L Johnson et al.
Physiology & behavior, 107(5), 733-742 (2012-05-05)
Although the hypothalamic orexin system is known to regulate appetitive behaviors and promote wakefulness and arousal (Sakurai, 2007 [56]), this system may also be important in adaptive and pathological anxiety/stress responses (Suzuki et al., 2005 [4]). In a recent study
View All Related Papers

Global Trade Item Number

SKUGTIN
E006-100MG04061832556413
E006-500MG04061832556420

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