Skip to Content
Merck
All Photos(1)

Documents

D7938

Sigma-Aldrich

DBO-83

solid

Synonym(s):

3-(6-Chloro-3-pyridazinyl)-3,8-diazabicyclo[3.2.1]octane dihydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H13ClN4 · 2HCl
CAS Number:
195211-53-1
Molecular Weight:
297.61
MDL number:
MFCD03452917
UNSPSC Code:
12352202
PubChem Substance ID:
24278387
NACRES:
NA.77

form

solid

solubility

H2O: 38 mg/mL

SMILES string

Cl.Cl.Clc1ccc(nn1)N2C[C@@H]3CC[C@H](C2)N3

InChI

1S/C10H13ClN4.2ClH/c11-9-3-4-10(14-13-9)15-5-7-1-2-8(6-15)12-7;;/h3-4,7-8,12H,1-2,5-6H2;2*1H/t7-,8+;;

InChI key

FMBGHZXNKMHVDT-QFHMQQKOSA-N

Gene Information

human ... CHRNA1(1134) , CHRNA10(57053) , CHRNA2(1135) , CHRNA3(1136) , CHRNA4(1137) , CHRNA5(1138) , CHRNA6(8973) , CHRNA7(1139) , CHRNA9(55584) , CHRNB1(1140) , CHRNB2(1141) , CHRNB3(1142) , CHRNB4(1143)

Biochem/physiol Actions

Novel nicotinic acetylcholine receptor agonist, structurally related to epibatidine, with antinociceptive properties in rodents.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ghelardini, C., et al.
Drug Development Research, 40, 251-258 (1997)
Neuronal nicotinic acetylcholine receptors as novel drug targets.
G K Lloyd et al.
The Journal of pharmacology and experimental therapeutics, 292(2), 461-467 (2000-01-20)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service