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About This Item
Empirical Formula (Hill Notation):
C19H25NO·HCl
CAS Number:
Molecular Weight:
319.87
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
To inquire about this product D2571, please contact your local Merck office or dealer. Contact Technical Service
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white
solubility
H2O: 16 mg/mL
storage temp.
2-8°C
SMILES string
Cl.CCN(CC)CCOc1ccc(Cc2ccccc2)cc1
InChI
1S/C19H25NO.ClH/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17;/h5-13H,3-4,14-16H2,1-2H3;1H
InChI key
TXLHNFOLHRXMAU-UHFFFAOYSA-N
Biochem/physiol Actions
DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site.
DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site. DPPE is a tamoxifen derivataive that binds with high affinity to the anti-estrogen binding site, but unlike tamoxifen, does not bind to the estrogen receptor. DPPE sensitizes MDR tumor cells to chemotherapy and also inhibits histamine binding at the intracellular histamine site.
Features and Benefits
This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility H2O: 16 mg/mL | solubility H2O: 15 mg/mL, clear | solubility DMSO: 10 mg/mL, clear | solubility H2O: 1 mg/mL, clear (warmed) |
| color white | color white to beige | color white to beige | color white to beige |
Storage Class
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| D2571-25MG | 04061832867052 |
| D2571-5MG | 04061832867069 |



