TK6

95111735, human lymph, Not specified

• Synonym(s): H2BT Cells, TK-6 Cells
• UNSPSC Code: 41106514

Properties

• Product Name: TK6, 95111735
• biological source: human lymph
• growth mode: Suspension
• karyotype: Not specified
• morphology: Not specified
• products: Not specified
• receptors: Not specified
• technique(s): cell culture | mammalian: suitable
• shipped in: dry ice
• storage temp.: −196°C

Description

Cell Line Origin

Human lymphoblast, thymidine kinase heterozygote

Cell Line Description

The thymidine kinase heterozygote cell line TK6 has been isolated from the lymphoblastoid line HH4. HH4 was derived from the WIL-2 cell line. TK6 cells are CD19 positive, 50% of the cell population express CD20 and a small sub-population has been tested positive for CD22. We cannot confirm the BVDV status of this cell line.

Application

Bromodeoxyuridine resistant assays

TK-6 cell line has been used to study the in vitro genotoxic effects of trans- and cis-2-ethylhexyl 4-methoxycinnamate (EHMC).[1] It has also been used to study the interaction of silver nanomaterials with the cells.[2]

DNA Profile

STR-PCR Data: Amelogenin: X,Y
CSF1PO: 11,12
D13S317: 11
D16S539: 11,12
D5S818: 12,13
D7S820: 9,11
THO1: 8,9.3
TPOX: 8,11
vWA: 17,20

Culture Medium

RPMI 1640 + 2mM Glutamine + 10% Horse Serum (HS) or FBS.

Subculture Routine

Maintain cultures between 1-9 x 100,000 cells/ml; 5% CO₂; 37°C.

Other Notes

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