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Coelenterazine hcp

Name: Coelenterazine hcp
Brand: SIGMA
Price: 5230 CZK

≥95% (HPLC), solid

Synonym(s):

CLZN-hcp

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Pack Size	SKU	Availability	Price
50 μg		Please contact Customer Service for Availability	CZK 5,230.00

About This Item

Empirical Formula (Hill Notation):

C₂₅H₂₅N₃O₂

CAS Number:

123437-32-1

Molecular Weight:

399.48

UNSPSC Code:

12352204

PubChem Substance ID:

24892609

NACRES:

NA.83

MDL number:

MFCD03453204

CZK 5,230.00

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Properties

Product Name

Coelenterazine hcp, solid

assay

≥95% (HPLC)

Quality Level

200

form

solid

solubility

methanol: 1 mg/mL, clear, yellow to orange

storage temp.

−20°C

SMILES string

Oc1ccc(cc1)C2=CN3C(=O)C(Cc4ccccc4)=NC3=C(CC5CCCC5)N2

InChI

1S/C25H25N3O2/c29-20-12-10-19(11-13-20)23-16-28-24(21(26-23)14-17-8-4-5-9-17)27-22(25(28)30)15-18-6-2-1-3-7-18/h1-3,6-7,10-13,16-17,26,29H,4-5,8-9,14-15H2

InChI key

YEGCUOQUFAXCMK-UHFFFAOYSA-N

Description

General description

Coelenterazine hcp is a semisynthetic analog of coelenterazine.[1]

Application

Coelenterazine hcp has been used:

as a component of coelenterazine reagent in the reporter assay[2]
in the purification of Renilla luciferase-labeled Annexin V[3]
in evaluating the activity of aequorin in Escherichia coli[4]

Biochem/physiol Actions

Coelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine[5] and a faster response time than native coelenterazine.[4]

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Show Differences

1 of 1

This Item	C3105	C2855	C3230
Sigma-Aldrich C3355 Coelenterazine hcp	Sigma-Aldrich C3105 Coelenterazine fcp	Sigma-Aldrich C2855 Coelenterazine cp	Sigma-Aldrich C3230 Coelenterazine h
assay ≥95% (HPLC)	assay ≥95% (HPLC)	assay -	assay -
solubility methanol: 1 mg/mL, clear, yellow to orange	solubility methanol: 1 mg/mL	solubility -	solubility -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form solid	form solid	form solid	form solid
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Retrospective on the development of aequorin and aequorin-based imaging to visualize changes in intracellular free [Ca(2+) ].

Sarah E Webb et al.

Molecular reproduction and development, 82(7-8), 563-586 (2014-01-03)

In this review, we take a retrospective look at the discovery and utilization of the Ca(2+) -sensitive bioluminescent protein complex, aequorin. We do consider the contribution it has made to our understanding of the natural phenomenon of bioluminescence, but it

Design and characterization of an aequorin-based bacterial biosensor for detection of toluene and related compounds.

Mehdi Zeinoddini et al.

Photochemistry and photobiology, 86(5), 1071-1075 (2010-07-29)

An aequorin-based Escherichia coli strain JM109 biosensor was constructed and characterized for its potential to detect toluene and related compounds in aqueous solutions. The biosensor was constructed based on a PGL2 plasmid carrying the lower pathway promoter (Pu) of the

Renilla luciferase-labeled Annexin V: a new probe for detection of apoptotic cells.

Mahboobeh Nazari et al.

The Analyst, 137(21), 5062-5070 (2012-09-25)

The Ca(2+)-dependent binding of Annexin V to phosphatidylserine on cell surfaces is a reliable marker for apoptosis that is widely used in flow cytometry based apoptosis assays. In this paper, we report a new class of Annexin V-based probes for

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Global Trade Item Number

SKU	GTIN
C3355-25UG	04061831157604
C3355-50UG	04061833384183

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