Skip to Content
Merck

C2832

Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride

≥95%, Cholesterol derivative, powder

Synonym(s):

3β-[N-(Dimethylaminoethane)­carbamoyl]­cholesterol, DC-Chol

Slide 1 of 2
Sign In to View Organizational & Contract Pricing.

Select a Size

25 MG

CZK 3,070.00

100 MG

CZK 9,990.00

CZK 3,070.00

Please contact Customer Service for Availability
​
Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):
C32H57ClN2O2
CAS Number:
166023-21-8
Molecular Weight:
537.26
UNSPSC Code:
12352200
PubChem Substance ID:
24892536
NACRES:
NA.77
MDL number:
MFCD00467173
Assay:
≥95%
Form:
powder
Quality level:
200

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride, ≥95%

Quality Level

200

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

Cl[H].[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(=O)NCCN(C)C)[C@H](C)CCCC(C)C

InChI

1S/C32H56N2O2.ClH/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5;/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35);1H/t23-,25+,26+,27-,28+,29+,31+,32-;/m1./s1

InChI key

ISXSJGHXHUZXNF-LXZPIJOJSA-N

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
C725992243228111
Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride ≥95%

Sigma-Aldrich

C2832

Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride

Cholesteryl erucate ≥95%

Sigma-Aldrich

C7259

Cholesteryl erucate

Cholesteryl N-(2-dimethylaminoethyl)carbamate ≥98% (TLC)

Sigma-Aldrich

92243

Cholesteryl N-(2-dimethylaminoethyl)carbamate

Cholesterol, Highly Purified Suitable for use in liposome preparations.

Sigma-Aldrich

228111

Cholesterol, Highly Purified

form

powder

form

powder

form

powder or crystals

form

powder

assay

≥95%

assay

≥95%

assay

≥98% (TLC)

assay

≥90% (HPLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

10-30°C

Application

This cationic cholesterol derivative forms liposomes with L-α-phosphatidylethanolamine, dioleoyl, that efficiently transfect mammalian cell lines.
Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride has been used as a bilayer-membrane stabiliser[1] and for nucleic acid transfer.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000522652
0000521712
0000521712
0000522652
0000497148

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Gene Targeting Protocols (2000)
A Colosimo et al.
Biochimica et biophysica acta, 1419(2), 186-194 (1999-07-17)
We evaluated the transfection efficiency of five different cationic liposome/plasmid DNA complexes, during the in vitro gene transfer into human epithelial tracheal cell lines. A dramatic correlation between the transfection efficiency and the charge ratio (positive charge of liposome to
P S Ajmani et al.
Neurochemical research, 24(5), 699-703 (1999-05-27)
Cationic lipid formulations consisting of 3beta [N-(N', N'-dimethylaminoethane)-carbamoyl] cholesterol (DC-Chol) and the helper lipid dioleoylphosphatidylethanolamine (DOPE) (1.5: 1 molar ratio) were prepared by solvent evaporation and sized by high pressure extrusion. Liposomes made of 1:1 molar ratio 1 ,2-dioleoyl-3-trimethyl-ammonium-propane (DOTAP)/DOPE
S Szala et al.
Gene therapy, 3(11), 1026-1031 (1996-11-01)
An attempt was made to use simple cationic liposomes DC-Chol/DOPE and DDAB/DOPE (DC-Chol is 3 beta (N(N',N-dimethylaminoethane) carbamoyl) cholesterol, DDAB is dimethyldioctadecyl ammonium bromide and DOPE is dioleoylphosphatidylethanolamine) for transfer of Escherichia coli cytosine deaminase 'suicide' gene under the control
M J Campbell
BioTechniques, 18(6), 1027-1032 (1995-06-01)
Cationic liposomes are being utilized for the delivery of DNA into mammalian cells both in vitro and in vivo. In this report, we describe a rapid, simple injection method for the preparation of cationic liposomes that requires no special equipment.
View All Related Papers

Global Trade Item Number

SKUGTIN
C2832-100MG04061833269688
C2832-25MG04061833269695

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service