B2432

8-Bromoadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer

≥98% (HPLC), solid

• Synonym(s): Rp-8-Br-cAMPS
• Empirical Formula (Hill Notation): C₁₀H₁₀BrN₅O₅PSNa
• Molecular Weight: 446.15
• NACRES: NA.77
• UNSPSC Code: 41106305
• Assay: ≥98% (HPLC)
• Form: solid

Properties

• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: solid
• packaging: vial of 5 μmol
• solubility: water: soluble
• storage temp.: −20°C

Description

Biochem/physiol Actions

Competitive inhibitor of cyclic AMP-dependent protein kinase A (PKA) type I and II. Membrane-permeable analog of the cAMP inhibitor Rp-cAMPS (Prod. No. A-165).

Features and Benefits

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)