A3355

ATC0175

≥98% (HPLC), solid

• Synonym(s): N-(cis-4-{[4-(Dimethylamino)quinazolin-2-yl]amino}cyclohexyl)-3,4-difluorobenzamide HCl
• Empirical Formula (Hill Notation): C₂₃H₂₆ClF₂N₅O
• CAS Number: 510733-97-8
• Molecular Weight: 461.94
• NACRES: NA.77
• PubChem Substance ID: 24724389
• UNSPSC Code: 51111800
• MDL number: MFCD08276913
• Assay: ≥98% (HPLC)
• Form: solid
• Quality level: 100

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• solubility: DMSO: soluble 5 mg/mL, H₂O: insoluble
• storage temp.: 2-8°C
• SMILES string: Cl[H].CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c3ccc(F)c(F)c3)nc4ccccc14
• InChI: 1S/C23H25F2N5O.ClH/c1-30(2)21-17-5-3-4-6-20(17)28-23(29-21)27-16-10-8-15(9-11-16)26-22(31)14-7-12-18(24)19(25)13-14;/h3-7,12-13,15-16H,8-11H2,1-2H3,(H,26,31)(H,27,28,29);1H/t15-,16+;
• InChI key: HUUPKFUYSQNNLO-FAESNJTISA-N

Description

Biochem/physiol Actions

ATC0175 is a non-peptide, orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist.

Non-peptide, orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist.

Features and Benefits

This compound is featured on the Melanin-Concentrating Hormone Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335,H413
• pcodes: P273 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves