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Anti-A_2A Adenosine Receptor antibody produced in rabbit

Name: Anti-A<SUB>2A</SUB> Adenosine Receptor antibody produced in rabbit
Brand: SIGMA
Price: 16000 CZK

affinity isolated antibody, buffered aqueous solution

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Pack Size	SKU	Availability	Price
100 μL		Please contact Customer Service for Availability	CZK 16,000.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01321632

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC (f), IP, WB

Citations:

CZK 16,000.00

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biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~45 kDa

species reactivity

canine, human

should not react with

rat

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Show Differences

1 of 1

This Item	SAB4500423	AB1559P	SAB4500549
Sigma-Aldrich A269 Anti-A_2A Adenosine Receptor antibody produced in rabbit	Sigma-Aldrich SAB4500423 Anti-ADORA2A antibody produced in rabbit	Sigma-Aldrich AB1559P Anti-Adenosine A2a Receptor Antibody	Sigma-Aldrich SAB4500549 Anti-ADRA2A antibody produced in rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity purified immunoglobulin	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate -	conjugate unconjugated
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
mol wt antigen ~45 kDa	mol wt antigen 44 kDa	mol wt -	mol wt antigen 48 kDa
species reactivity canine, human	species reactivity human	species reactivity pig, bovine, canine, human	species reactivity human

General description

ADORA2A is an adenosine receptor and part of the G-protein coupled receptor family of proteins. ADORA2A is involved in regulating myocardial blood flow and dopamine release in the brain.

Anti-A2A Adenosine Receptor is specific for A2A adenosine receptor adenosine receptor subtype. By immunoblotting, it reacts strongly with canine A2A. However, it does not react with rat A2A. The antibody detects A2A adenosine receptor in human hippocampus by immunohistology and may be used for immunoprecipitation.

Immunogen

Synthetic peptide (Ser-His-Gly-Asp-Met-Gly-Leu-Pro-Asp-Val-Glu-Leu-Leu-Ser-His-Glu-Leu-Lys) derived from amino acids 373-391 of the canine A_2A adenosine receptor C-terminal domain.

Application

Rabbit anti-A2A adenosine receptor antibody can be used for western blot applications. The antibody can also be used for immunohistochemistry (1:100, frozen sections) and immunoprecipitation applications.

Physical form

Solution in phosphate buffered saline, containing 1 mg/ml BSA and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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alpha 2-Adrenoceptors potentiate angiotensin II- and vasopressin-induced renal vasoconstriction in spontaneously hypertensive rats.

Liping Gao et al.

The Journal of pharmacology and experimental therapeutics, 305(2), 581-586 (2003-02-28)

Hypertension in spontaneously hypertensive rats (SHRs) is due in part to enhanced effects of vasoactive peptides on the renal vasculature. We hypothesize that the G(i) signal transduction pathway enhances renovascular responses to vasoactive peptides in SHRs more so than in

Adenosine receptor distribution in Rhesus monkey ocular tissue.

Krista M Beach et al.

Experimental eye research, 174, 40-50 (2018-05-25)

Adenosine receptor (ADOR) antagonists, such as 7-methylxanthine (7-MX), have been shown to slow myopia progression in humans and animal models. Adenosine receptors are found throughout the body, and regulate the release of neurotransmitters such as dopamine and glutamate. However, the

Global Trade Item Number

SKU	GTIN
A269-100UL	04061837829697

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