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Merck

A0144

Adenosine 3′,5′-cyclic monophosphate–Agarose

lyophilized powder

Synonym(s):

3′,5′-cAMP agarose

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1 ML

CZK 3,070.00

5 ML

CZK 10,400.00

CZK 3,070.00


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About This Item

UNSPSC Code:
41106500
eCl@ss:
32160414
NACRES:
NA.56
MDL number:
Form:
lyophilized powder
Storage temp.:
−20°C

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form

lyophilized powder

extent of labeling

≥2 μmol per mL

matrix

4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

C-8

matrix spacer

9 atoms

storage temp.

−20°C

Quality Level

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This Item
A2810G9768A2767
Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

lyophilized powder

form

lyophilized powder

form

aqueous glycerol suspension

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

extent of labeling

≥2 μmol per mL

extent of labeling

1-5 μmol per mL

extent of labeling

1-5 μmol per mL

extent of labeling

1-5 μmol per mL

matrix

4% beaded agarose

matrix

cross-linked 4% beaded agarose

matrix

cross-linked 4% beaded agarose

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix activation

cyanogen bromide

matrix activation

cyanogen bromide

matrix activation

cyanogen bromide

Application

Adenosine 3′,5′-cyclic monophosphate-Agarose (3′,5′-cAMP agarose) may be used in affinity chromatography for the separation of the subunits of cAMP-dependent protein kinase or for the purification of the cAMP receptor subunit. Research on schizophrenia has shown that abnormalities in the cAMP signaling pathway, may contribute to the pathophysiology of the disorder.

Physical form

Lyophilized powder stabilized with lactose

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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M Meyer et al.
Journal of bacteriology, 183(18), 5248-5256 (2001-08-22)
Klebsiella pneumoniae is able to grow anaerobically with citrate as a sole carbon and energy source by a fermentative pathway involving the Na(+)-dependent citrate carrier CitS, citrate lyase, and oxaloacetate decarboxylase. The corresponding genes are organized in the divergent citC
K Laukens et al.
FEBS letters, 508(1), 75-79 (2001-11-15)
The soluble protein fraction of tobacco bright yellow 2 cells contained adenosine 3',5'-cyclic monophosphate (cAMP)-binding activity, detected with both a conventional binding assay and a surface plasmon resonance biosensor. A cAMP-agarose-based affinity purification procedure yielded three proteins which were identified
R G Panchal et al.
The Journal of biological chemistry, 269(38), 23722-23730 (1994-09-23)
cAMP-dependent protein kinase (PKA) is an important participant in neuronal modulation: the ability of neurons to change their properties in response to external stimuli. In Aplysia mechanosensory neurons, PKA plays roles in both short and long term presynaptic facilitation, which
Purification of rabbit skeletal muscle protein kinase regulatory subunit using cyclic adenosine-3':5'-monophosphate affinity chromatography.
W L Dills et al.
Biochemical and biophysical research communications, 62(1), 70-77 (1975-01-06)
Purification of the cAMP receptor protein by affinity chromatography.
J Ramseyer et al.
Biochemical and biophysical research communications, 59(2), 813-821 (1974-07-24)

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