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49549

4-Hydroxy-L-isoleucine

≥98.0% (TLC)

Synonym(s):

(2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid

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10 mg
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CZK 2,110.00
50 mg
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CZK 8,430.00

About This Item

Empirical Formula (Hill Notation):
C6H13NO3
CAS Number:
781658-23-9
Molecular Weight:
147.17
UNSPSC Code:
12352204
eCl@ss:
32160406
PubChem Substance ID:
329757475
NACRES:
NA.32
MDL number:
MFCD06799350

CZK 2,110.00

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Product Name

4-Hydroxy-L-isoleucine, ≥98.0% (TLC)

Quality Level

100

assay

≥98.0% (TLC)

optical activity

[α]/D +34.0±2.0°, c = 1 in H2O

color

white to off-white

storage temp.

2-8°C

SMILES string

CC(O)[C@H](C)[C@H](N)C(O)=O

InChI

1S/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t3-,4?,5-/m0/s1

InChI key

OSCCDBFHNMXNME-DSDZBIDZSA-N

Biochem/physiol Actions

A peculiar amino acid extracted from fenugreek seeds and never found in mammalian tissues, exhibits interesting insulinotropic activity; effects on insulin secretion[1], plant-derived treatment for metabolic syndrome[2].

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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1 of 1

This Item
5011858879I7634
4-Hydroxy-L-isoleucine ≥98.0% (TLC)

Sigma-Aldrich

49549

4-Hydroxy-L-isoleucine

(4S)-4-Hydroxy-L-isoleucine from fenugreek seeds, ≥98.0% (TLC)

Sigma-Aldrich

50118

(4S)-4-Hydroxy-L-isoleucine

L-Isoleucine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

58879

L-Isoleucine

D-Isoleucine ≥98% (TLC)

Sigma-Aldrich

I7634

D-Isoleucine

assay

≥98.0% (TLC)

assay

≥98.0% (TLC)

assay

≥99.5% (NT), ≥99.5% (TLC)

assay

≥98% (TLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

optical activity

[α]/D +34.0±2.0°, c = 1 in H2O

optical activity

[α]/D +32.5±2.0°, c = 1 in H2O

optical activity

[α]20/D +41.0±1°, c = 5% in 6 M HCl

optical activity

-

color

white to off-white

color

white to almost white

color

white

color

white

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

296.6 °F

flash_point_c

147 °C

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL4680
BCCH0483
BCBZ5523
BCBW2694
BCBV8225

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C Broca et al.
European journal of pharmacology, 390(3), 339-345 (2000-03-10)
4-Hydroxyisoleucine, a peculiar amino acid extracted from fenugreek seeds and never found in mammalian tissues, exhibits interesting insulinotropic activity. To investigate the structural requirements for this stimulating effect, the insulinotropic activity of the major isomer (2S,3R,4S) of 4-hydroxyisoleucine, in the
Choong Tat Keng et al.
Gut, 65(10), 1744-1753 (2015-07-08)
HCV infection affects millions of people worldwide, and many patients develop chronic infection leading to liver cancers. For decades, the lack of a small animal model that can recapitulate HCV infection, its immunopathogenesis and disease progression has impeded the development
Anna Maria Herzner et al.
PloS one, 6(7), e22389-e22389 (2011-08-04)
Lantibiotics are small peptide antibiotics that contain the characteristic thioether amino acids lanthionine and methyllanthionine. As ribosomally synthesized peptides, lantibiotics possess biosynthetic gene clusters which contain the structural gene (lanA) as well as the other genes which are involved in
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Global Trade Item Number

SKUGTIN
49549-50MG04061832415604
49549-10MG04061832719238

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