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45124

Elastase from porcine pancreas

powder, white, ≥10 U/mg

Synonym(s):

Elastase from hog pancreas, Pancreatopeptidase E

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About This Item

CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
254-453-6
MDL number:
EC Number:
Specific activity:
≥10 U/mg
Biological source:
Porcine pancreas


biological source

Porcine pancreas

form

powder

specific activity

≥10 U/mg

mol wt

Mr ~25000

color

white

storage temp.

−20°C

Biochem/physiol Actions

Elastase hydrolyses elastin, the specific protein of elastic fibers, and digests hemoglobin, casein and fibrin.

Other Notes

1 U corresponds to the amount of enzyme which liberates 1 μmol 4-nitroaniline per minute at 25°C and pH 7.8 (succinyl-(L-Ala)3-4-nitroanilide as substrate)
One unit will hydrolyze 1.0 μmole of N-succinyl-L-Ala-Ala-Ala-p-nitroanilide per min, pH 8.0 at 25 °C.
Sales restrictions may apply
Cleaves polyalanyl-lysine peptides at the alanyl-lysine bond, review; Review, elastase-type proteases[1]


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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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D. Atlas et al.
Proc. 13th Eur. Pept. Symp.: Peptides 1974, 361-361 (1975)
Huanlei Zhu et al.
International journal of clinical and experimental pathology, 12(4), 1260-1271 (2020-01-15)
The formation and rupture of aneurysms is a reversible process involving the destruction and repair of smooth muscle cells, and the proliferation of vascular smooth muscle cells (VSMC) and inflammation play an important role. In our study, we investigated whether
L Robert
Pathologie-biologie, 36(9), 1101-1107 (1988-11-01)
Elastin in the most resistant fibrous protein of the organisms. Its degradation is catalysed by proteases designated as elastases. Elastic fibers appeared during phylogenesis at the level of the first Vertebrates and rendered possible the emergence of efficient circulatory and



Global Trade Item Number

SKUGTIN
45124-10MG04061832324128

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