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About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
254-453-6
MDL number:
Specific activity:
≥10 U/mg
Biological source:
Porcine pancreas
biological source
Porcine pancreas
form
powder
specific activity
≥10 U/mg
mol wt
Mr ~25000
color
white
storage temp.
−20°C
Biochem/physiol Actions
Elastase hydrolyses elastin, the specific protein of elastic fibers, and digests hemoglobin, casein and fibrin.
Other Notes
1 U corresponds to the amount of enzyme which liberates 1 μmol 4-nitroaniline per minute at 25°C and pH 7.8 (succinyl-(L-Ala)3-4-nitroanilide as substrate)
One unit will hydrolyze 1.0 μmole of N-succinyl-L-Ala-Ala-Ala-p-nitroanilide per min, pH 8.0 at 25 °C.
Sales restrictions may apply
Cleaves polyalanyl-lysine peptides at the alanyl-lysine bond, review; Review, elastase-type proteases[1]
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signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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D. Atlas et al.
Proc. 13th Eur. Pept. Symp.: Peptides 1974, 361-361 (1975)
Huanlei Zhu et al.
International journal of clinical and experimental pathology, 12(4), 1260-1271 (2020-01-15)
The formation and rupture of aneurysms is a reversible process involving the destruction and repair of smooth muscle cells, and the proliferation of vascular smooth muscle cells (VSMC) and inflammation play an important role. In our study, we investigated whether
L Robert
Pathologie-biologie, 36(9), 1101-1107 (1988-11-01)
Elastin in the most resistant fibrous protein of the organisms. Its degradation is catalysed by proteases designated as elastases. Elastic fibers appeared during phylogenesis at the level of the first Vertebrates and rendered possible the emergence of efficient circulatory and
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 45124-10MG | 04061832324128 |

