46429

Methimazole

VETRANAL^®, analytical standard

• Synonym(s): 1-Methyl-2-imidazolethiol, 2-Mercapto-1-methylimidazole
• Empirical Formula (Hill Notation): C₄H₆N₂S
• CAS Number: 60-56-0
• Molecular Weight: 114.17
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329757178
• EC Number: 200-482-4
• Beilstein/REAXYS Number: 108646
• MDL number: MFCD00179321

Properties

• grade: analytical standard
• Quality Segment: 200
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• mp: 144-147 °C (lit.)
• application(s): cleaning products; clinical; cosmetics; food and beverages; forensics and toxicology; personal care; pharmaceutical (small molecule)
• format: neat
• SMILES string: CN1C=CNC1=S
• InChI: 1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
• InChI key: PMRYVIKBURPHAH-UHFFFAOYSA-N
• Gene Information: human ... TPO(7173)

Description

General description

Methimazole is a thyreostatic compound, and an antihormone, which is widely used in medicine for the treatment of hyperthyroidism.

Application

Methimazole may be used as a reference standard for the determination of the analyte in fish homogenates using mixed mode solid-phase extraction technique with reversed-phase high-performance liquid chromatography method with ultraviolet detection (MMSPE-RP-HPLC-UV).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08,GHS07
• pcodes: P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• target_organs: Endocrine system
• signalword: Danger
• hcodes: H302,H317,H319,H360D,H373
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 1A - Skin Sens. 1 - STOT RE 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects