32402

Sulfaguanidine

VETRANAL^®, analytical standard

• Synonym(s): 4-Amino-N-(aminoiminomethyl)benzenesulfonamide, 4-Amino-N-guanylbenzenesulfonamide
• Empirical Formula (Hill Notation): C₇H₁₀N₄O₂S
• CAS Number: 57-67-0
• Molecular Weight: 214.24
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329754181
• EC Number: 200-345-9
• Beilstein/REAXYS Number: 2695326
• MDL number: MFCD00038136

Properties

• grade: analytical standard
• Quality Segment: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• SMILES string: NC(=N)NS(=O)(=O)c1ccc(N)cc1
• InChI: 1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)
• InChI key: BRBKOPJOKNSWSG-UHFFFAOYSA-N

Description

General description

Sulfaguanidine belongs to the sulfonamide class of antibiotics. It can exhibit broad-spectrum inhibition of both gram-positive and gram-negative bacteria.

Chemical structure: sulfonamide

Application

Sulfaguanidine may be used as an analytical reference standard for the determination of sulfaguanidine in:

• Food samples of animal origin by salting-out supported liquid extraction (SOSLE) and quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction followed by analysis using nanoflow liquid chromatography high resolution mass spectrometry (LC-HRMS).
• Bovine muscle samples by hydrophilic interaction liquid chromatography-electrospray-tandem mass spectrometry (HILIC-ESI-MS/MS) equipped with selected reaction monitoring (SRM) mode of detection.
• Tissues, milk and eggs of food producing animals by ultrasound-assisted extraction (UAE), solid phase extraction (SPE) and LC-MS/MS.
• Beeswax by solid-liquid extraction (SLE), liquid-liquid extraction (LLE), SPE, QuEChERS extraction and ESI-LC-MS/MS with SRM detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3