00920

N-Acetyl-L-aspartic acid

≥99.0% (T)

• Synonym(s): (2S)-2-Acetamidobutanedioic acid, N-Acetyl-S-aspartic acid
• Linear Formula: HO₂CCH₂CH(NHCOCH₃)CO₂H
• CAS Number: 997-55-7
• Molecular Weight: 175.14
• NACRES: NA.22
• PubChem Substance ID: 329747163
• eCl@ss: 32160406
• UNSPSC Code: 12352209
• MDL number: MFCD00020500
• Beilstein/REAXYS Number: 1726198
• Assay: ≥99.0% (T)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥99.0% (T)
• form: powder
• optical activity: [α]20/D +12±1°, c = 2% in 6 M HCl
• reaction suitability: reaction type: solution phase peptide synthesis
• color: colorless to white
• mp: 137-140 °C (lit.), 141-146 °C
• application(s): peptide synthesis
• SMILES string: CC(=O)N[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C6H9NO5/c1-3(8)7-4(6(11)12)2-5(9)10/h4H,2H2,1H3,(H,7,8)(H,9,10)(H,11,12)/t4-/m0/s1
• InChI key: OTCCIMWXFLJLIA-BYPYZUCNSA-N

Description

Application

N-Acetyl-L-aspartic acid can be used as a reactant to synthesize:

• Protected homoserine γ-lactones by selective reduction and acid-catalyzed cyclization reaction.
• Racemic amino substituted succinimide derivatives via cyclocondensation reaction.

Other Notes

Review; acetyl donor in acetylcholine formation in brain.[1]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)