MAB8599

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A

clone 131-2A, Chemicon^®, from mouse

• Synonym(s): RSV Fusion
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Clone: 131-2A, monoclonal
• Species reactivity: human
• Application: ELISA, FACS, IF, WB
• Citations: 48

Properties

• biological source: mouse
• Quality Segment: 300
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 131-2A, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable, flow cytometry: suitable, immunofluorescence: suitable, western blot: suitable
• isotype: IgG2aκ
• shipped in: wet ice

Description

General description

RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.

~70 kDa

Immunogen

A2 RSV virus cell extract

Epitope: all type A & B strains

Application

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A detects level of Respiratory Syncytial Virus & has been published & validated for use in ELISA, FC, IF & WB.

Indirect immunofluorescence.

ELISA

Immunoblotting: (using purified F protein preparations, clone identified a ~70kDa band, Tripp, RA et al 2003)

Final working dilutions must be determined by end user.

Research Category
Infectious Diseases

Research Sub Category
Infectious Diseases - Viral

Biochem/physiol Actions

Reacts with RSV fusion protein, specifically epitope F1a of RSV F-protein {Sominina AA, et al Vestn Ross Akad Med Nauk. 1995;(9):49-54} found on all A & B strains of RSV.

Physical form

Format: Purified

Protein A Purified immunoglobulin in 0.02M phosphate, 0.25M NaCl, 0.1% NaN3 pH 7.6

Protein A purified

Preparation Note

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
RSV Control Slides, Catalogue Number 5012-5

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable