ABC350

Anti-CIDE-A Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IF, IHC, WB
• Citations: 1

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: mouse
• technique(s): immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable
• UniProt accession no.: O70302
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: mouse ... Cidea(12683)

Description

General description

Cell death activator CIDE-A (CIDE-A) binds to lipid droplets and regulates their enlargement which restricts lipolysis and favoring storage. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. CIDE-A is highly expressed in brown adipose tissue and, at lower levels, in white adipose tissue.

~25 kDa observed

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of mouse CIDE-A.

Application

Detect CIDE-A using this rabbit polyclonal antibody, Anti-CIDE-A Antibody validated for use in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected CIDE-A in mouse heart tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected CIDE-A in mouse heart tissue.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Biochem/physiol Actions

This antibody recognizes the C-terminus of CIDE-A.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse heart tissue lysate

Evaluated by Western Blotting in mouse heart tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected CIDE-A in 15 µg of mouse heart tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable