AB3244

Anti-GLP-1 (7-36) Antibody, CT amide-reactive

serum, Chemicon^®

• Synonym(s): Glucagon-like peptide-1
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA, RIA
• Citations: 2

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• should not react with: guinea pig
• species reactivity (predicted by homology): mammals
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable, radioimmunoassay: suitable
• NCBI accession no.: NM_002054.2
• UniProt accession no.: P01275
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... GCG(2641)

Description

Immunogen

Epitope: C-terminus amide-reactive

Whole synthetic peptide.

Application

Anti-GLP-1 (7-36) Antibody, C-terminus amide-reactive detects level of GLP-1 (7-36) & has been published & validated for use in ELISA, RIA.

RIA: 1:300,000. Ka = 0.8 x 10E12 l/mol for GLP-1(7-36) amide. Detection limit 0.1 fmol/tube, 95% confidence limits.

EIA (capture). Detection limit 1.5 pmol/liter.

Note: Plasma samples require extraction for RIA, but not for sandwich EIA. Optimal working dilutions must be determined by end user.

Research Category
Metabolism

Research Sub Category
Metabolic Hormones & Receptors

Biochem/physiol Actions

Glucagon-like peptide-1(7-36) amide (GLP-1), C-terminal reactive. Cross-reacts fully with GLP-1(1-36) amide but shows <0.1% cross reactivity with the unamidated forms GLP-1(7-37) and GLP-1(1-37) or other related peptides such as hGLP-2, glucagon, hGIP and VIP.

SPECIES REACTIVITIES: Most mammalian species. GLP-1 is identical in all mammalian species studied except guinea pig and presumably its South American rodent relatives.

Physical form

Rabbit serum, diluted. Liquid in PBS containing 0.05% sodium azide.

Preparation Note

Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• Storage Class: 12 - Non Combustible Liquids