AB1975

Anti-Enkephalin, Met Antibody

serum, Chemicon^®

• Synonym(s): Anti-PE, Anti-PENK-A
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC
• Citations: 3

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: rat
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable
• suitability: not suitable for Western blot
• UniProt accession no.: P01210
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: rat ... Penk(29237)

Description

General description

0.6 kDa

Met Enkephalin is an endogenous opioid peptide neurotransmitter found naturally in the brains of many animals, including humans. Methionine enkephalin (Met Enkephalin) is a pentapeptide that appears to enhance immune function at low doses and suppress at high doses. This molecule acts in the central nervous, neuroendocrine, and immune systems. During development of the brain Met Enkephalin is thought to act as a growth factor. Met Enkephalin may be capable of enhancing immune function in cancer or AIDS patients.

Immunogen

Met-enkephalin, Hemocyanin conjugate.

Application

Immunohistochemistry (with immunoperoxidase detection *): 48 hour incubation, 4°C.

Spinal cord nerve fibers (rat): 1:2,000-1:4,000.

Immunofluorescence*: overnight incubation, +2-8°C

Duodenum endocrine cells & nerve fibers (pig): 1:2,000

Ileum endocrine cells & nerve fibers μguinea pig): 1:4,000.

*fixative-any cross-linking reagent

Optimal working dilutions must be determined by the end user.

Research Category
Neuroscience

Research Sub Category
Neuroinflammation & Pain

Hormones & Receptors

This Anti-Enkephalin, Met Antibody is validated for use in IH for the detection of Enkephalin.

Biochem/physiol Actions

Met-enkephalin

Physical form

Serum in 0.05% Sodium Azide

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Tested on rat brain/coronal section

Other Notes

Replaces: AB5026

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 1