693015

Zwittergent^® 3-12 Detergent

A synthetic zwitterionic detergent, which unlike other amphoteric surfactants, retains its zwitterionic character over a broad pH range.

• Synonym(s): n-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate, hplc solvents
• Empirical Formula (Hill Notation): C₁₇H₃₇NO₃S
• CAS Number: 14933-08-5
• Molecular Weight: 335.55
• UNSPSC Code: 12161902
• NACRES: NA.25
• MDL number: MFCD00036909

Properties

• Quality Segment: 100
• assay: ≥99% (TLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated
• aggregation number: 55
• color: white
• CMC: 2 - 4 mM
• solubility: water: 5%
• shipped in: ambient
• storage temp.: 15-25°C
• SMILES string: [S](=O)(=O)([O-])CCC[N+](CCCCCCCCCCCC)(C)C
• InChI: 1S/C17H37NO3S/c1-4-5-6-7-8-9-10-11-12-13-15-18(2,3)16-14-17-22(19,20)21/h4-17H2,1-3H3
• InChI key: IZWSFJTYBVKZNK-UHFFFAOYSA-N

Description

General description

A synthetic zwitterionic detergent, which unlike other amphoteric surfactants, retains its zwitterionic character over a broad pH range. This property is attributed to the presence of both a strongly basic quaternary ammonium ion and an acidic sulfonate ion of equal strength. This ionic balance presumably prevents irreversible binding to either anionic or cationic compounds.

Application

• Characterization for the Similarity Assessment between Proposed Biosimilar SB12 and Eculizumab Reference Product Using a State-of-the-Art Analytical Method.: The study characterizes the similarity between biosimilar SB12 and Eculizumab, employing Zwittergent^® 3-12 Detergent for accurate protein analysis (Kim et al., 2023).

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Raper, S.E., et al. 1992. Hepatology16, 433.
Nollstadt, K.H., et al. 1989. J. Chromatogr.497, 87.
Byers, S., et al. 1987. J. Biol. Chem.262, 9166.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Zwittergent is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Corrosive (L)

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup