627609

Caspase Inhibitor I

InSolution

• Synonym(s): InSolution Caspase Inhibitor I
• Empirical Formula (Hill Notation): C₂₂H₃₀FN₃O₇
• Molecular Weight: 467.49
• NACRES: NA.54
• UNSPSC Code: 12352200
• Form: liquid
• Storage condition: OK to freeze, protect from light

Properties

• Quality Segment: 100
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• shipped in: wet ice
• storage temp.: −20°C

Description

General description

When using with a purified recombinant enzyme, pretreatment with an esterase is required.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Fas-mediated apoptosis in Jurkat cells and staurosporine-induced cell death in corneal epithelial cells

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Physical form

A 10 mM (1 mg in 214 µl) solution of Caspase Inhibitor I Cat. No. 627610 in DMSO.

Preparation Note

Following initial thaw, aliquot, purge with inert gas, and freeze(-20°C).

Analysis Note

Single spot by TLC

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: 188.6 °F - (refers to pure substance)
• flash_point_c: 87 °C - (refers to pure substance)