The buffer is phosphate-buffered saline (PBS) at a pH of approximately 7 ± 0.2, containing 0.1% bovine serum albumin (BSA). For dilution, it is recommended to use buffers that contain protein, such as 0.1% BSA.
407293
α-Interferon, Mouse, Recombinant, E. coli
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 kU | Estimated to ship onMay 22, 2026fromAreál Kühne+Nagel spol. s r.o. | CZK 20,100.00 |
About This Item
NACRES:
NA.32
UNSPSC Code:
12352202
Form:
liquid
Assay:
≥95% (SDS-PAGE)
description
Merck USA index - 14, 4990
Quality Level
assay
≥95% (SDS-PAGE)
form
liquid
specific activity
≥3.5 x 104 units/mL
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
shipped in
wet ice
storage temp.
−70°C
General description
Recombinant, mouse α-interferon expressed in E. coli. Antiviral, antineoplastic agent. Expressed during the triggering stage of macrophage cytocidal activation. Suppresses bone marrow function and cell proliferation. Modulates the immune response. Also known to induce apoptotic cell death in non-melanoma skin cancer.
Other Notes
Krishnan, K., et al. 1997. Eur. J. Biochem. 247, 298.
Rodriquez-Villanueva, S., and McDonnel, T.J. 1995. Int. J. Cancer61, 110.
Dianzani, F. 1993. Gut34, 574.
Brouty-Boyce, D., and Zetter, B.R. 1990. Science208, 516.
Sidky, Y.A., and Borden, E.C. 1987. Cancer Res.47, 5155.
Daugherty, B.L., and Pestka, S. 1986. Methods Enzymol.119, 34.
Pestka, S. 1986. Methods Enzymol.119, 14.
Familletti, P.C., et al. 1981. Methods Enzymol.78, 387.
Johnson, M.D., et al. 1981. Methods Enzymol.78, 394.
Rubinstein, S., et al. 1981. J. Virol.37, 755.
Rodriquez-Villanueva, S., and McDonnel, T.J. 1995. Int. J. Cancer61, 110.
Dianzani, F. 1993. Gut34, 574.
Brouty-Boyce, D., and Zetter, B.R. 1990. Science208, 516.
Sidky, Y.A., and Borden, E.C. 1987. Cancer Res.47, 5155.
Daugherty, B.L., and Pestka, S. 1986. Methods Enzymol.119, 34.
Pestka, S. 1986. Methods Enzymol.119, 14.
Familletti, P.C., et al. 1981. Methods Enzymol.78, 387.
Johnson, M.D., et al. 1981. Methods Enzymol.78, 394.
Rubinstein, S., et al. 1981. J. Virol.37, 755.
One unit of interferon per ml of medium will cause a 50% inhibition of EMCV-induced cytopathic effect on mouse L929 cells. Units are determined with respect to the NIH international reference standard for mouse IFN-α.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥95% (SDS-PAGE) | assay ≥95% (RP-HPLC, FPLC, and SDS-PAGE) | assay ≥97% (SDS-PAGE) | assay ≥95% (SDS-PAGE) |
| form liquid | form lyophilized | form lyophilized | form liquid |
| shipped in wet ice | shipped in wet ice | shipped in ambient | shipped in wet ice |
| storage temp. −70°C | storage temp. −20°C | storage temp. −70°C | storage temp. −20°C |
| storage condition OK to freeze, avoid repeated freeze/thaw cycles | storage condition OK to freeze, desiccated | storage condition OK to freeze | storage condition OK to freeze, avoid repeated freeze/thaw cycles |
| specific activity ≥3.5 x 104 units/mL | specific activity - | specific activity - | specific activity - |
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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W Markland et al.
Antimicrobial agents and chemotherapy, 44(4), 859-866 (2000-03-18)
The enzyme IMP dehydrogenase (IMPDH) catalyzes an essential step in the de novo biosynthesis of guanine nucleotides, namely, the conversion of IMP to XMP. The major event occurring in cells exposed to competitive IMPDH inhibitors such as ribavirin or uncompetitive
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 407293-100KU | 04055977188196 |
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In what buffer is the interferon? what is the pH? if one needs to dilute, what is your recommendation?
1 answer-
Helpful?
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