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324628

EGTA/AM

Membrane-permeable form of the Ca2+-chelating agent EGTA.

Synonym(s):

EGTA/AM, Ethyleneglycol- bis(β-aminoethyl)-N,N,Nʹ,Nʹ-tetraacetoxymethyl Ester, Ethyleneglycol-bis(β-aminoethyl)-N,N,Nʹ,Nʹ-tetraacetoxymethyl Ester

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Pack SizeSKUAvailabilityPrice
10 mg

Available to ship TODAYfromAreál Kühne+Nagel spol. s r.o.

CZK 9,790.00

About This Item

Empirical Formula (Hill Notation):
C26H40N2O18
CAS Number:
Molecular Weight:
668.60
MDL number:
UNSPSC Code:
12352108
NACRES:
NA.25

CZK 9,790.00


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Quality Segment

assay

≥95% (HPLC)

form

oil

reaction suitability

reagent type: chelator

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

light yellow

solubility

DMSO: 20 mg/mL, DMF: soluble

shipped in

ambient

storage temp.

−20°C

SMILES string

N(CCOCCOCCN(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

InChI

1S/C26H40N2O18/c1-19(29)39-15-43-23(33)11-27(12-24(34)44-16-40-20(2)30)5-7-37-9-10-38-8-6-28(13-25(35)45-17-41-21(3)31)14-26(36)46-18-42-22(4)32/h5-18H2,1-4H3

InChI key

GNJXVFXIDHCCKR-UHFFFAOYSA-N

General description

Membrane-permeable form of the Ca2+-chelating agent EGTA.
Membrane-permeable version of the Ca2+-chelating agent EGTA (Cat. No. 324625). Induces apoptosis in pheochromocytoma (PC12) cells.

Application


  • Arresting calcium-regulated sperm metabolic dynamics enables prolonged fertility in poultry liquid semen storage.: Researchers explored the effects of calcium regulation on sperm metabolism, demonstrating that EGTA/AM can arrest calcium dynamics, significantly enhancing the storage and fertility of poultry semen. This finding could have broad implications for agricultural practices and poultry breeding programs (Sushadi et al., 2023).

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Garcia, J.G., et al. 1992. Blood79, 2056.
Kuriyama, S., et al. 1992. Brain Res.579, 227.
Maki, A., et al. 1992. FASEB J.6, 919.
Negre-Salvayre, A., and Salvayre, R. 1992. Biochim. Biophys. Acta 1123, 207.
Ichinose, M., et al. 1992. Biochem. Biophys. Res. Commun.182, 372.
Hong, M., and Moody, T.W. 1991. Peptides12, 1315.
Schnellmann, R.G. 1991. J. Biochem. Toxicol.6, 299.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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This Item
324626196419616394
assay

≥95% (HPLC)

assay

≥98% dry basis (complexometric)

assay

≥90% (TLC)

assay

≥97% (titration)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

10-30°C

storage temp.

−20°C

storage temp.

15-25°C

form

oil

form

solid (fine)

form

solid

form

solid

solubility

DMSO: 20 mg/mL, DMF: soluble

solubility

1 M NaOH: soluble

solubility

DMSO: 10 mg/mL

solubility

ethanol: 10 mg/mL, 0.1 M phosphate pH 7.0: 25 μM, DMSO: soluble

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Global Trade Item Number

SKUGTIN
324628-10MG04055977196719

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