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309795

DIDS disodium salt

≥85% (HPLC), solid, anion transport inhibitor, Calbiochem®

Synonym(s):

DIDS, Disodium Salt, 4,4ʹ-Diisothiocyanostilbene-2,2ʹ-disulfonic Acid, 2Na

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Pack SizeSKUAvailabilityPrice
250 mg

Available to ship TODAYfromAreál Kühne+Nagel spol. s r.o.

CZK 4,850.00

About This Item

Empirical Formula (Hill Notation):
C16H8N2O6S4 · 2Na
CAS Number:
Molecular Weight:
498.48
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥85% (HPLC)
Form:
solid
Storage condition:
OK to freeze, desiccated, protect from light

CZK 4,850.00


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Product Name

DIDS, Disodium Salt, Binds covalently and irreversibly to the outer surface of human erythrocyte membranes.

Quality Segment

assay

≥85% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated, protect from light

color

yellow

solubility

water: 0.5%

shipped in

ambient

storage temp.

−20°C

SMILES string

[S](=O)(=O)(O)c1c(ccc(c1)N=C=S)\C=C\c2c(cc(cc2)N=C=S)[S](=O)(=O)O

InChI

1S/C16H10N2O6S4/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24/h1-8H,(H,19,20,21)(H,22,23,24)/b2-1+

InChI key

YSCNMFDFYJUPEF-OWOJBTEDSA-N

General description

Binds covalently and irreversibly to the outer surface of human erythrocyte membrane proteins. Inhibits ATP transport into the endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl- uptake (IC50 = 150 nM) in neuroblastoma cells. Has antiulcerous activity.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Cl- uptake
Product does not compete with ATP.
Reversible: no
Target IC50: 150 nM inhibiting Cl- uptake in neuroblastoma cells

Other Notes

Bettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol.15, 207.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

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This Item
525276233183506600
assay

≥85% (HPLC)

assay

-

assay

≥97% (titration)

assay

≥98% (HPLC)

form

solid

form

lyophilized solid

form

solid

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage condition

OK to freeze, protect from light, desiccated

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze, desiccated (hygroscopic)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
309795-250MG04055977216790

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