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264151

Caspase-3 Substrate VII, Fluorogenic

Fluorogenic caspase-3 substrate.

Synonym(s):

Caspase-3 Substrate VII, Fluorogenic, Ac-DEVD-AFC

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1 mg

Available to ship TODAYfromAreál Kühne+Nagel spol. s r.o.

CZK 3,070.00
5 mg

Estimated to ship onMay 15, 2026fromAreál Kühne+Nagel spol. s r.o.

CZK 10,900.00

About This Item

Empirical Formula (Hill Notation):
C30H34F3N5O13
Molecular Weight:
729.61
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
lyophilized solid
Quality level:
100
Storage condition:
OK to freeze, desiccated, protect from light

CZK 3,070.00

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Quality Level

100

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated, protect from light

color

white

solubility

DMSO: 5 mg/mL

fluorescence

λex ~400 nm, λem ~505 nm

shipped in

ambient

storage temp.

−20°C

General description

Fluorogenic caspase-3 substrate (excitation maximum: ~400 nm; emission maximum: ~505 nm). Also acts as a substrate for granzyme B-processed ICE-LAP3, caspase-6, caspase-7, caspase-8, and caspase-10.
Fluorogenic caspase-3 substrate. Also acts as a substrate for granzyme B-processed caspase-6, caspase-7, caspase-8, and caspase-10.

Biochem/physiol Actions

Reversible: no
Cell permeable: no
Primary Target
Fluorogenic caspase-3 substrate
Product does not compete with ATP.

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Ac-Asp-Glu-Val-Asp-AFC
Keramaris, E., et al. 2000. Mol. Cell Neurosci. 15, 368.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Caspase-3 Substrate VII, Fluorogenic Fluorogenic caspase-3 substrate.

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Caspase-3 Substrate II, Fluorogenic

Caspase-1 Substrate X, Fluorogenic A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.

Sigma-Aldrich

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Caspase-1 Substrate X, Fluorogenic

Caspase-3 Substrate IV, Fluorogenic Fluorogenic caspase-3 substrate.

Sigma-Aldrich

264150

Caspase-3 Substrate IV, Fluorogenic

form

lyophilized solid

form

solid

form

lyophilized

form

solid

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: 5 mg/mL

solubility

DMSO: 10 mM

solubility

DMSO: 5 mg/mL

solubility

DMSO: 10 mg/mL

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
264151-5MG04055977198430
264151-1MG04055977198423

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