233152

Dithioerythritol

A protective agent for SH groups.

• Synonym(s): Dithioerythritol, Cleland’s Other Reagent, DTE
• Empirical Formula (Hill Notation): C₄H₁₀O₂S₂
• CAS Number: 6892-68-8
• Molecular Weight: 154.25
• UNSPSC Code: 12161504
• NACRES: NA.25
• MDL number: MFCD00063750

Properties

• Quality Segment: 100
• description: RTECS - KF2410000
• assay: ≥98% (titration)
• form: solid
• reaction suitability: reagent type: reductant
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• impurities: <1% disulfides (UV)
• color: white
• pH: 4.5-6.5 (25 °C, 15.4 g/L)
• solubility: water: 50 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: SC[C@H](O)[C@H](O)CS
• InChI: 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+
• InChI key: VHJLVAABSRFDPM-ZXZARUISSA-N

Description

General description

A protective agent for SH groups.

Water-soluble, cell-permeable protective reagent for sulfhydryl groups. Maintains monothiols in the reduced state and reduces disulfides quantitatively. Protects protein sulfhydryls and restores enzyme activity lost by the oxidation of sulfhydryl groups in vitro.

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 2 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H412
• pcodes: P264 - P270 - P273 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3