14-935-M
GRK1, active
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| Size/SKU | Availability | Price |
|---|---|---|
250 μg | Estimated to ship onJune 05, 2026fromAreál Kühne+Nagel spol. s r.o. | CZK 88,500.00 |
About This Item
UNSPSC Code:
12352204
NACRES:
NA.32
eCl@ss:
32160405
Biological source:
human
CZK 88,500.00
Estimated to ship onJune 05, 2026Details
General description
Product Source: N-terminal 6His-tagged, recombinant, human GRK1 full length, expressed by baculovirus in Sf21 insect cells
Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
Biochem/physiol Actions
Target Sub-Family: AGC
Packaging
Also available in 250μg size as catalog # 14-935M and in bulk as catalog # 14-935-K.
Physical form
Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Purified using immobilized metal affinity chromatography.
Preparation Note
6 months at -70°C
Analysis Note
Routinely evaluated by phosphorylation of KKKKERLLDDRHDSGLDSMKDEE
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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This Item | |||
|---|---|---|---|
| biological source human | biological source - | biological source - | biological source - |
| technique(s) activity assay: suitable (kinase) | technique(s) - | technique(s) - | technique(s) - |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. - | UniProt accession no. - |
| mol wt Mw 68 kDa | mol wt ~95 kDa | mol wt ~89 kDa | mol wt ~93 kDa |
| NCBI accession no. | NCBI accession no. | NCBI accession no. | NCBI accession no. |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level - |
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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