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![[6]-Gingerol, Zingiber officinale An antitumor, apoptosis-inducing compound of the ginger family that blocks EGF-induced cell transformation by inhibiting the activation of Activator Protein-1 (AP-1).](/deepweb/assets/sigmaaldrich/product/images/140/919/0846df46-0b67-4c28-b99d-87e177be65b2/640/0846df46-0b67-4c28-b99d-87e177be65b2.jpg)
biological source
Zingiber officinale Roscoe
grade
FG
natural
reg. compliance
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
refractive index
n20/D 1.527
application(s)
flavors and fragrances
Documentation
see Safety & Documentation for available documents
food allergen
no known allergens
Organoleptic
ginger
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Asp. Tox. 1 - Skin Sens. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
154.4 °F - closed cup
Flash Point(C)
68 °C - closed cup
Certificates of Analysis (COA)
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M T Ortega et al.
Journal of applied toxicology : JAT, 36(2), 189-198 (2015-05-16)
We developed an in vitro method to assess pet food ingredients safety. Canine bone marrow-derived mesenchymal stem cells (BMSC) were differentiated into enterocyte-like cells (ELC) to assess toxicity in cells representing similar patterns of exposure in vivo. The toxicological profile
Azam Hosseinzadeh et al.
Cells, tissues, organs, 204(5-6), 241-250 (2017-09-07)
The protective effects of ginger (Zingiber officinale Roscoe) extract on IL-1β-mediated oxidative stress and mitochondrial apoptosis were investigated in C28I2 human chondrocytes. The effects of various concentrations of ginger extract on C28I2 human chondrocyte viability were evaluated in order to
Young-Soo Kim et al.
International journal of molecular medicine, 38(6), 1905-1914 (2016-11-15)
Ginger extract is used as an analeptic in herbal medicine and has been reported to exert antioxidant effects. Transient receptor potential (TRP) canonical 5 (TRPC5), TRP cation channel, subfamily M, member 7 (TRPM7; melastatin 7), and TRP cation channel, subfamily A, member 1 (TRPA1; ankyrin 1) are non-selective cation channels that are
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